Domains within Drosophila melanogaster protein CDC42_DROME (P40793)

Cdc42 homolog

Alternative representations: 1 /

Protein length191 aa
Source databaseUniProt
Identifiers CDC42_DROME, P40793, FBPP0301153, FBPP0301154, FBPP0074520, Q540W4, Q9U9S3, Q9U9S4, Q9U9S5, Q9U9S6, Q9V465, M9NFF8_DROME, M9NFF8
Source gene FBgn0010341

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

CDC42_DROME is shown as Cdc42 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cdc42

Protein CDC42_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05132Salmonella infection
map05135Yersinia infection
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K07904RAB11ARas-related protein Rab-11A
K04392RAC1Ras-related C3 botulinum toxin substrate 1
K04393CDC42cell division control protein 42

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0301153 in eggNOG.

OGTaxonomic classDescription
LCOG1100All organisms (root)Ras-related protein Rab-11A,Ras-related C3 botulinum toxin substrate 1,ADP-ribosylation factor 1/2
EJ3Q8Endopterygota (cohort)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42
FE3TBmelanogaster subgroup (species subgroup)cell division control protein 42
FV5IGmelanogaster group (species group)cell division control protein 42
KOG0393Eukaryota (superkingdom)Ras-related C3 botulinum toxin substrate 1,Ras homolog gene family, member A,cell division control protein 42
HU2A1Metazoa (kingdom)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42,Ras homolog gene family, member G
HIG2ZArthropoda (phylum)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42,Ras homolog gene family, member U
864C3Hexapoda (subphylum)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42
AHNVVNeoptera (infraclass)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42
ANRJFDiptera (order)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42
7GHQYOpisthokonta (clade)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42,Ras homolog gene family, member G
H4ZIXBilateria (clade)Ras-related C3 botulinum toxin substrate 1,cell division control protein 42,Ras homolog gene family, member G
EH1U5Drosophila (genus)cell division control protein 42
50J0ZSophophora (subgenus)cell division control protein 42

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: