Domains within Homo sapiens protein ID1_HUMAN (P41134)

DNA-binding protein inhibitor ID-1

Alternative representations: 1 /

Protein length155 aa
Source databaseUniProt
Identifiers ID1_HUMAN, P41134, ENSP00000365280.3, ENSP00000365280, A8K537, E1P5L4, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109, H2RDX7_PANTR, H2RDX7, G3RJ48_GORGO, G3RJ48
Source gene ENSG00000125968
Alternative splicing ID1_HUMAN, P41134-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ID1_HUMAN is shown as ID1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ID1

Protein ID1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04350TGF-beta signaling pathway

KEGG orthologous groups

KONameDescription
K17693ID2DNA-binding protein inhibitor ID2
K04680ID1DNA-binding protein inhibitor ID1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 14 PTMs annotated in this protein:

PTMCount
Ubiquitination8
Phosphorylation6

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSPTRG00000013357.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000365280 in eggNOG.

OGTaxonomic classDescription
6WSX2All organisms (root)DNA-binding protein inhibitor ID2,DNA-binding protein inhibitor ID1,DNA-binding protein inhibitor ID4
5JPJ0Eukaryota (superkingdom)DNA-binding protein inhibitor ID2,DNA-binding protein inhibitor ID1,DNA-binding protein inhibitor ID4
HTWYNMetazoa (kingdom)DNA-binding protein inhibitor ID1
94WUQChordata (phylum)DNA-binding protein inhibitor ID1
5QARQSarcopterygii (superclass)DNA-binding protein inhibitor ID1
8YVAMMammalia (class)DNA-binding protein inhibitor ID1
4R6DJEuarchontoglires (superorder)DNA-binding protein inhibitor ID1
503IAPrimates (order)DNA-binding protein inhibitor ID1
98MWYHaplorrhini (suborder)DNA-binding protein inhibitor ID1
BUYRVSimiiformes (infraorder)DNA-binding protein inhibitor ID1
9EVT0Catarrhini (parvorder)DNA-binding protein inhibitor ID1
7NMVJOpisthokonta (clade)DNA-binding protein inhibitor ID1,DNA-binding protein inhibitor ID2
9FWDHVertebrata (clade)DNA-binding protein inhibitor ID1
H6KJGBilateria (clade)DNA-binding protein inhibitor ID1
FWY8IHominoidea (superfamily)DNA-binding protein inhibitor ID1
5NBB1Hominidae (family)DNA-binding protein inhibitor ID1
5XYMRHomininae (subfamily)DNA-binding protein inhibitor ID1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: