Domains within Mus musculus protein BCL6_MOUSE (P41183)

B-cell lymphoma 6 protein homolog

Alternative representations: 1 /

Protein length707 aa
Source databaseUniProt
Identifiers BCL6_MOUSE, P41183, ENSMUSP00000023151.5, ENSMUSP00000023151, Q61065, Q544F9_MOUSE, Q544F9
Source gene ENSMUSG00000022508

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

BCL6_MOUSE is shown as Bcl6 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Bcl6

Protein BCL6_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05207Chemical carcinogenesis - receptor activation
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein
K15618BCL6B-cell lymphoma 6 protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 8 PTMs annotated in this protein:

PTMCount
Phosphorylation8

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Bcl6.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000023151 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HU1A6Metazoa (kingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,IKAROS family zinc finger protein
93E82Chordata (phylum)B-cell CLL/lymphoma 6 member B protein,B-cell lymphoma 6 protein,chromatin complexes subunit BAP18
5QFT2Sarcopterygii (superclass)B-cell CLL/lymphoma 6 member B protein,B-cell lymphoma 6 protein,chromatin complexes subunit BAP18
8ZF5ZMammalia (class)B-cell lymphoma 6 protein
4RH33Euarchontoglires (superorder)B-cell lymphoma 6 protein
AIBNHRodentia (order)B-cell lymphoma 6 protein
8D93CMyomorpha (suborder)B-cell lymphoma 6 protein
H663FBilateria (clade)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,IKAROS family zinc finger protein
7MTDYOpisthokonta (clade)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
9G7IKVertebrata (clade)B-cell CLL/lymphoma 6 member B protein,B-cell lymphoma 6 protein,chromatin complexes subunit BAP18
CQ58KMuridae (family)B-cell lymphoma 6 protein
ADXSYMurinae (subfamily)B-cell lymphoma 6 protein
5PRZKMus (genus)B-cell lymphoma 6 protein
HE1NMMus (subgenus)B-cell lymphoma 6 protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: