Domains within Gallus gallus protein RAN_CHICK (P42558)

GTP-binding nuclear protein Ran

Alternative representations: 1 /

Protein length216 aa
Source databaseUniProt
Identifiers RAN_CHICK, P42558, ENSGALP00000047624.1, ENSGALP00000047624, ENSGALP00000054241.1, ENSGALP00000054241, F6Z673, H0Z2P1_TAEGU, H0Z2P1, A0A1L1RZU0_CHICK, A0A1L1RZU0, A0A1V4JTV0_PATFA, A0A1V4JTV0, G0ZE55_ALLMI, G0ZE55, Q0PHC9_SALSA, Q0PHC9, A0A091UNE2_NIPNI, A0A091UNE2, A0A091J7R7_CALAN, A0A091J7R7, A0A093HCX0_STRCA, A0A093HCX0, A0A091GDW9_9AVES, A0A091GDW9, A0A091TWW2_PHORB, A0A091TWW2, A0A093PPD1_9PASS, A0A093PPD1, A0A091SPS4_NESNO, A0A091SPS4, A0A093NLF6_PYGAD, A0A093NLF6, A0A093FGA0_GAVST, A0A093FGA0, A0A091TDM0_PHALP, A0A091TDM0, A0A091PRA0_LEPDC, A0A091PRA0, A0A099ZCL3_TINGU, A0A099ZCL3, A0A0A0ARU8_CHAVO, A0A0A0ARU8, A0A091JAP0_EGRGA, A0A091JAP0, A0A091K284_COLST, A0A091K284, A0A093CRZ7_TAUER, A0A093CRZ7, A0A094L7L6_9AVES, A0A094L7L6, A0A087QSK9_APTFO, A0A087QSK9, A0A091NY29_HALAL, A0A091NY29, A0A087VB88_BALRE, A0A087VB88, A0A091EQT2_CORBR, A0A091EQT2, A0A093QIP0_PHACA, A0A093QIP0, A0A094KLQ0_ANTCR, A0A094KLQ0, A0A093L2N5_EURHL, A0A093L2N5, A0A093FV52_TYTAL, A0A093FV52, A0A091W0G8_OPIHO, A0A091W0G8, A0A091LYZ3_CARIC, A0A091LYZ3, F6Z673_MONDO, K7FXN7_PELSI, K7FXN7, B5FYI0_TAEGU, B5FYI0, U3K4L6_FICAL, U3K4L6, A0A1U7RFN2_ALLSI, A0A1U7RFN2, U3J1N9_ANAPL, U3J1N9, A0A226PY06_COLVI, A0A226PY06, A0A218UDG3_9PASE, A0A218UDG3
Source gene ENSGALG00000002569
Alternative splicing RAN_CHICK, A0A1L1RKL2_CHICK, ENSGALP00000064376.1, A0A1I7Q3Y7_CHICK

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

RAN_CHICK is shown as RAN in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RAN

Protein RAN_CHICK is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03250Viral life cycle - HIV-1

KEGG orthologous groups

KONameDescription
K07936RANGTP-binding nuclear protein Ran

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 32 PTMs annotated in this protein:

PTMCount
Ubiquitination16
Phosphorylation7
Acetylation7
Nitrosylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSMODG00000015601.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9031.ENSGALP00000054241 in eggNOG.

OGTaxonomic classDescription
LKOG0096All organisms (root)GTP-binding nuclear protein Ran,adhesion G protein-coupled receptor B3,adhesion G-protein coupled receptor D1
KOG0096Eukaryota (superkingdom)GTP-binding nuclear protein Ran,adhesion G protein-coupled receptor B3,adhesion G-protein coupled receptor D1
HVXCFMetazoa (kingdom)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
9416CChordata (phylum)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
5QF2RSarcopterygii (superclass)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
6BDP6Aves (class)GTP-binding nuclear protein Ran
8R8WVNeognathae (infraclass)GTP-binding nuclear protein Ran
BIWXHGalloanserae (superorder)GTP-binding nuclear protein Ran
AJ34QGalliformes (order)GTP-binding nuclear protein Ran
9GUP4Vertebrata (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
H3YM4Bilateria (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
7H5M4Opisthokonta (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
86WP4Phasianidae (family)GTP-binding nuclear protein Ran
926R6Phasianinae (subfamily)GTP-binding nuclear protein Ran

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: