Domains within Drosophila melanogaster protein SNRPA_DROME (P43332)

U1 small nuclear ribonucleoprotein A

Alternative representations: 1 /

Protein length216 aa
Source databaseUniProt
Identifiers SNRPA_DROME, P43332, FBPP0070716, Q9W4D7, K7Z580_DROME, K7Z580
Source gene FBgn0003449

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

SNRPA_DROME is shown as snf in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for snf

Protein SNRPA_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome

KEGG orthologous groups

KONameDescription
K11094SNRPB2U2 small nuclear ribonucleoprotein B''

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 13 PTMs annotated in this protein:

PTMCount
Ubiquitination9
Acetylation3
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein snf.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0070716 in eggNOG.

OGTaxonomic classDescription
FUXRVmelanogaster group (species group)U2 small nuclear ribonucleoprotein B''
FDVHFmelanogaster subgroup (species subgroup)U2 small nuclear ribonucleoprotein B''
EJ3ZDEndopterygota (cohort)U2 small nuclear ribonucleoprotein B''
LKOG4206All organisms (root)U2 small nuclear ribonucleoprotein B'',U11/U12 small nuclear ribonucleoprotein 65 kDa protein,U1 small nuclear ribonucleoprotein A
KOG4206Eukaryota (superkingdom)U2 small nuclear ribonucleoprotein B'',U11/U12 small nuclear ribonucleoprotein 65 kDa protein,U1 small nuclear ribonucleoprotein A
HTF8PMetazoa (kingdom)U1 small nuclear ribonucleoprotein A,U2 small nuclear ribonucleoprotein B''
HIIWTArthropoda (phylum)U1 small nuclear ribonucleoprotein A,U2 small nuclear ribonucleoprotein B''
85AB7Hexapoda (subphylum)U2 small nuclear ribonucleoprotein B''
AGWP5Neoptera (infraclass)U2 small nuclear ribonucleoprotein B''
ANHD5Diptera (order)U2 small nuclear ribonucleoprotein B''
7KTHXOpisthokonta (clade)U1 small nuclear ribonucleoprotein A,U2 small nuclear ribonucleoprotein B''
H51QMBilateria (clade)U1 small nuclear ribonucleoprotein A,U2 small nuclear ribonucleoprotein B''
EGVBKDrosophila (genus)U2 small nuclear ribonucleoprotein B''
50FRHSophophora (subgenus)U2 small nuclear ribonucleoprotein B''

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: