Domains within Drosophila melanogaster protein RB27C_DROME (P48809)

Heterogeneous nuclear ribonucleoprotein 27C

Alternative representations: 1 /

Protein length421 aa
Source databaseUniProt
Identifiers RB27C_DROME, P48809, FBPP0078975, FBPP0078974, FBPP0297874, FBPP0297875, FBPP0290617, FBPP0078976, FBPP0297873, FBPP0290618, A4V0B8, Q7JPT5, Q9TY67, Q9VM68, E1JHA4_DROME, E1JHA4
Source gene FBgn0004838

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

RB27C_DROME is shown as Hrb27C in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Hrb27C

Protein RB27C_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03015mRNA surveillance pathway

KEGG orthologous groups

KONameDescription
K14411MSIRNA-binding protein Musashi

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 13 PTMs annotated in this protein:

PTMCount
Phosphorylation13

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Hrb27C.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0297875 in eggNOG.

OGTaxonomic classDescription
EIND2Endopterygota (cohort)RNA-binding protein Musashi
FV4XEmelanogaster group (species group)RNA-binding protein Musashi
LKOG4205All organisms (root)RNA-binding protein Musashi,squid,heterogeneous nuclear ribonucleoprotein A1/A3
FE14Gmelanogaster subgroup (species subgroup)RNA-binding protein Musashi
KOG4205Eukaryota (superkingdom)RNA-binding protein Musashi,squid,heterogeneous nuclear ribonucleoprotein A1/A3
HSR2UMetazoa (kingdom)RNA-binding protein Musashi
HIK5VArthropoda (phylum)RNA-binding protein Musashi
86CV5Hexapoda (subphylum)RNA-binding protein Musashi
AHT9HNeoptera (infraclass)RNA-binding protein Musashi
ANXRTDiptera (order)RNA-binding protein Musashi
7KXJ4Opisthokonta (clade)RNA-binding protein Musashi,heterogeneous nuclear ribonucleoprotein A0,heterogeneous nuclear ribonucleoprotein A1/A3
H4C59Bilateria (clade)RNA-binding protein Musashi
EH2ADDrosophila (genus)RNA-binding protein Musashi
50BQHSophophora (subgenus)RNA-binding protein Musashi

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: