Domains within Xenopus laevis protein RAN_XENLA (P52301)

GTP-binding nuclear protein Ran

Alternative representations: 1 /

Protein length216 aa
Source databaseUniProt
Identifiers Q7ZYT6, Q9IBE8, A0A1L8I0T9_XENLA, A0A1L8I0T9, RAN_XENLA, P52301

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

RAN_XENLA is shown as ran-2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ran-2

Protein RAN_XENLA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03250Viral life cycle - HIV-1

KEGG orthologous groups

KONameDescription
K07936RANGTP-binding nuclear protein Ran

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 8355.A0A1L8I0T9 in eggNOG.

OGTaxonomic classDescription
LKOG0096All organisms (root)GTP-binding nuclear protein Ran,adhesion G protein-coupled receptor B3,adhesion G-protein coupled receptor D1
KOG0096Eukaryota (superkingdom)GTP-binding nuclear protein Ran,adhesion G protein-coupled receptor B3,adhesion G-protein coupled receptor D1
HVXCFMetazoa (kingdom)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
9416CChordata (phylum)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
5QF2RSarcopterygii (superclass)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
9GUP4Vertebrata (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1
7H5M4Opisthokonta (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]
H3YM4Bilateria (clade)GTP-binding nuclear protein Ran,adhesion G-protein coupled receptor D1,N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: