Domains within Mus musculus protein RD23B_MOUSE (P54728)

UV excision repair protein RAD23 homolog B

Alternative representations: 1 /

Protein length416 aa
Source databaseUniProt
Identifiers RD23B_MOUSE, P54728, ENSMUSP00000030134.8, ENSMUSP00000030134, Q3TUA4, A0A0N8DTT2_9CRUS, A0A0N8DTT2
Source gene ENSMUSG00000028426

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

RD23B_MOUSE is shown as Rad23b in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Rad23b

Protein RD23B_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04141Protein processing in endoplasmic reticulum
map03420Nucleotide excision repair

KEGG orthologous groups

KONameDescription
K10839RAD23, HR23UV excision repair protein RAD23
K04523UBQLN, DSK2ubiquilin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 31 PTMs annotated in this protein:

PTMCount
Ubiquitination15
Phosphorylation13
Acetylation2
Caspase cleavage aspartic acid1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Rad23b.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000030134 in eggNOG.

OGTaxonomic classDescription
LCOG5272All organisms (root)ubiquilin,UV excision repair protein RAD23,ubiquitin-small subunit ribosomal protein S27Ae
KOG0011Eukaryota (superkingdom)UV excision repair protein RAD23,ubiquitin-like protein 4,calreticulin
HW6GTMetazoa (kingdom)UV excision repair protein RAD23
93MU8Chordata (phylum)UV excision repair protein RAD23
5QCY7Sarcopterygii (superclass)UV excision repair protein RAD23
8Z7X9Mammalia (class)UV excision repair protein RAD23
4R8DDEuarchontoglires (superorder)UV excision repair protein RAD23
AI6WBRodentia (order)UV excision repair protein RAD23
8D4GHMyomorpha (suborder)UV excision repair protein RAD23
H5JA5Bilateria (clade)UV excision repair protein RAD23
7J5NKOpisthokonta (clade)UV excision repair protein RAD23
9GNQAVertebrata (clade)UV excision repair protein RAD23
CQCXWMuridae (family)UV excision repair protein RAD23
AE4GEMurinae (subfamily)UV excision repair protein RAD23
5PWBKMus (genus)UV excision repair protein RAD23
HE4MQMus (subgenus)UV excision repair protein RAD23

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: