Domains within Homo sapiens protein INHBC_HUMAN (P55103)

Inhibin beta C chain

Alternative representations: 1 /

Protein length352 aa
Source databaseUniProt
Identifiers INHBC_HUMAN, P55103, ENSP00000308716.2, ENSP00000308716, A1L3Y2
Source gene ENSG00000175189

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eumetazoa

Predicted functional partners

INHBC_HUMAN is shown as INHBC in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for INHBC

Protein INHBC_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04350TGF-beta signaling pathway
map04060Cytokine-cytokine receptor interaction

KEGG orthologous groups

KONameDescription
K21283BMP2bone morphogenetic protein 2
K22688INHBCinhibin beta C chain

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein INHBC.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000308716 in eggNOG.

OGTaxonomic classDescription
LKOG3900All organisms (root)bone morphogenetic protein 2,bone morphogenetic protein 7,nodal
KOG3900Eukaryota (superkingdom)bone morphogenetic protein 2,bone morphogenetic protein 7,nodal
HTUETMetazoa (kingdom)inhibin beta C chain,inhibin beta E chain,inhibin beta B chain
93Q6KChordata (phylum)inhibin beta C chain,inhibin beta E chain,inhibin beta B chain
5QPEXSarcopterygii (superclass)inhibin beta C chain,inhibin beta E chain,inhibin beta B chain
8ZIB5Mammalia (class)inhibin beta C chain
4RDC7Euarchontoglires (superorder)inhibin beta C chain
4ZS9JPrimates (order)inhibin beta C chain
98FW4Haplorrhini (suborder)inhibin beta C chain
BVCG1Simiiformes (infraorder)inhibin beta C chain
9EP28Catarrhini (parvorder)inhibin beta C chain
7KD0MOpisthokonta (clade)inhibin beta C chain,inhibin beta E chain,inhibin beta B chain
H5DXRBilateria (clade)inhibin beta C chain,inhibin beta E chain,inhibin beta B chain
9G1GIVertebrata (clade)inhibin beta C chain,inhibin beta E chain,inhibin beta B chain
FXAJSHominoidea (superfamily)inhibin beta C chain
5MXQJHominidae (family)inhibin beta C chain
5XYSDHomininae (subfamily)inhibin beta C chain

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: