Domains within Rattus norvegicus protein CAD17_RAT (P55281)

Cadherin-17

Alternative representations: 1 /

Protein length827 aa
Source databaseUniProt
Identifiers CAD17_RAT, P55281, ENSRNOP00000021612.2, ENSRNOP00000021612
Source gene ENSRNOG00000015562

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

CAD17_RAT is shown as Cdh17 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cdh17

Protein CAD17_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05226Gastric cancer
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K16499PCDHD2protocadherin delta 2
K06811CDH17cadherin 17, LI cadherin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000021612 in eggNOG.

OGTaxonomic classDescription
LKOG3594All organisms (root)protocadherin delta 2,protocadherin delta 1,protocadherin beta
KOG3594Eukaryota (superkingdom)protocadherin delta 2,protocadherin delta 1,protocadherin beta
HTA71Metazoa (kingdom)cadherin 16, KSP-cadherin,cadherin 17, LI cadherin
93YAZChordata (phylum)cadherin 16, KSP-cadherin,cadherin 17, LI cadherin
5QRHWSarcopterygii (superclass)cadherin 17, LI cadherin
8YXNVMammalia (class)cadherin 17, LI cadherin
4RMI0Euarchontoglires (superorder)cadherin 17, LI cadherin
AI0P2Rodentia (order)cadherin 17, LI cadherin
8DE41Myomorpha (suborder)cadherin 17, LI cadherin
7HS63Opisthokonta (clade)cadherin 16, KSP-cadherin,cadherin 17, LI cadherin
9FXIJVertebrata (clade)cadherin 16, KSP-cadherin,cadherin 17, LI cadherin
H524KBilateria (clade)cadherin 16, KSP-cadherin,cadherin 17, LI cadherin
CQ4QXMuridae (family)cadherin 17, LI cadherin
ADYBKMurinae (subfamily)cadherin 17, LI cadherin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: