Domains within Homo sapiens protein WNT7B_HUMAN (P56706)

Protein Wnt-7b

Alternative representations: 1 /

Protein length349 aa
Source databaseUniProt
Identifiers WNT7B_HUMAN, P56706, ENSP00000341032.4, ENSP00000341032, B8A596, Q96Q12, A0A2I3TH72_PANTR, A0A2I3TH72, H2P4S1_PONAB, H2P4S1, A0A2K5VJD2_MACFA, A0A2K5VJD2, A0A0D9QZ47_CHLSB, A0A0D9QZ47, A0A2K6BRE8_MACNE, A0A2K6BRE8, A0A2K5P8S6_CERAT, A0A2K5P8S6, A0A096NKR7_PAPAN, A0A096NKR7, A0A2K5ZBV8_MANLE, A0A2K5ZBV8, A0A2I3HZL1_NOMLE, A0A2I3HZL1
Source gene ENSG00000188064
Alternative splicing WNT7B_HUMAN, A8K0G1_HUMAN, B8A595_HUMAN, B8A597_HUMAN, B8A598_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eumetazoa

Predicted functional partners

WNT7B_HUMAN is shown as WNT7B in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for WNT7B

Protein WNT7B_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K00572WNT7wingless-type MMTV integration site family, member 7

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 8 PTMs annotated in this protein:

PTMCount
Phosphorylation8

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein RP11-435J19.1-001.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000341032 in eggNOG.

OGTaxonomic classDescription
LKOG3913All organisms (root)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 2,wingless-type MMTV integration site family, member 5
KOG3913Eukaryota (superkingdom)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 2,wingless-type MMTV integration site family, member 5
HVSAQMetazoa (kingdom)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 5,wingless-type MMTV integration site family, member 8
94RCTChordata (phylum)wingless-type MMTV integration site family, member 7
5QJRXSarcopterygii (superclass)wingless-type MMTV integration site family, member 7
8YZSBMammalia (class)wingless-type MMTV integration site family, member 7
4R5ZTEuarchontoglires (superorder)wingless-type MMTV integration site family, member 7
4ZXE7Primates (order)wingless-type MMTV integration site family, member 7
98BZBHaplorrhini (suborder)wingless-type MMTV integration site family, member 7
BV7TQSimiiformes (infraorder)wingless-type MMTV integration site family, member 7
9F2EECatarrhini (parvorder)wingless-type MMTV integration site family, member 7
7IBPIOpisthokonta (clade)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 5,wingless-type MMTV integration site family, member 8
H47X0Bilateria (clade)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 5,wingless-type MMTV integration site family, member 2
9GTIEVertebrata (clade)wingless-type MMTV integration site family, member 7
FXDF0Hominoidea (superfamily)wingless-type MMTV integration site family, member 7
5NDA3Hominidae (family)wingless-type MMTV integration site family, member 7
5Y696Homininae (subfamily)wingless-type MMTV integration site family, member 7

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: