Domains within Homo sapiens protein RB11A_HUMAN (P62491)

Ras-related protein Rab-11A

Alternative representations: 1 /

Protein length216 aa
Source databaseUniProt
Identifiers RB11A_HUMAN, P62491, ENSP00000261890.2, ENSP00000261890, B2R4B6, B4DT13, P24410, Q5TZN9, Q9JLX1, RB11A_CANLF, P62490, K9KCI9_HORSE, K9KCI9, RB11A_MOUSE, P62492, Q3V1Z6, RB11A_PIG, Q52NJ1, RB11A_PONAB, Q5R9M7, RB11A_RABIT, P62493, RB11A_RAT, P62494, A0A024R5Z8_HUMAN, A0A024R5Z8, H2Q9M8_PANTR, H2Q9M8, F7HLD9_MACMU, F7HLD9, U3EZ12_CALJA, U3EZ12, G7P8V6_MACFA, G7P8V6, G3REC0_GORGO, G3REC0, F2Z4D5_BOVIN, F2Z4D5, H0WWR4_OTOGA, H0WWR4, A0A2J8T808_PONAB, A0A2J8T808, L5K0U3_PTEAL, L5K0U3, A0A0D9RKS9_CHLSB, A0A0D9RKS9, A0A2K6LIW0_RHIBE, A0A2K6LIW0, A0A2K6DWK6_MACNE, A0A2K6DWK6, L5LFP7_MYODS, L5LFP7, A0A2K5MAI2_CERAT, A0A2K5MAI2, M3WVD0_FELCA, M3WVD0, A0A2K6Q2A8_RHIRO, A0A2K6Q2A8, F6SG28_MONDO, F6SG28, A0A096NME5_PAPAN, A0A096NME5, A0A2K5BX68_AOTNA, A0A2K5BX68, S9X009_CAMFR, S9X009, A0A2K6S8M3_SAIBB, A0A2K6S8M3, A0A2K5IZY9_COLAP, A0A2K5IZY9, A0A2K5PU56_CEBCA, A0A2K5PU56, M3XMT5_MUSPF, M3XMT5, G3T7F3_LOXAF, G3T7F3, G5AN52_HETGA, G5AN52, Q0PD45_MOUSE, Q0PD45, A0A286X7V8_CAVPO, A0A286X7V8, A0A250YCL4_CASCN, A0A250YCL4, A0A1U7QY95_MESAU, A0A1U7QY95, I3MPF7_ICTTR, I3MPF7, G3I0B0_CRIGR, G3I0B0
Source gene ENSG00000103769
Alternative splicing B4DQU5_HUMAN, RB11A_HUMAN, H3BMH2_HUMAN, H3BSC1_HUMAN, ENSP00000456420.1, ENSP00000454673.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

RB11A_HUMAN is shown as RAB11A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RAB11A

Protein RB11A_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04962Vasopressin-regulated water reabsorption
map04144Endocytosis
map05132Salmonella infection
map04972Pancreatic secretion

KEGG orthologous groups

KONameDescription
K07904RAB11ARas-related protein Rab-11A

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 83 PTMs annotated in this protein:

PTMCount
Phosphorylation53
Ubiquitination18
Acetylation6
Prenylation6

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSMMUG00000008006.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000261890 in eggNOG.

OGTaxonomic classDescription
LCOG1100All organisms (root)Ras-related protein Rab-11A,Ras-related C3 botulinum toxin substrate 1,ADP-ribosylation factor 1/2
KOG0087Eukaryota (superkingdom)Ras-related protein Rab-11A,Ras-related protein Rab-11B,Rab-like protein 2
HSTHWMetazoa (kingdom)solute carrier family 39 (zinc transporter), member 1/2/3,Ras-related protein Rab-11B,Ras-related protein Rab-11A
94802Chordata (phylum)Ras-related protein Rab-11B,Ras-related protein Rab-11A
5RAQ1Sarcopterygii (superclass)Ras-related protein Rab-11B,Ras-related protein Rab-11A
8Z1DGMammalia (class)Ras-related protein Rab-11B,Ras-related protein Rab-11A
4R9ZPEuarchontoglires (superorder)Ras-related protein Rab-11A,Ras-related protein Rab-11B
502ABPrimates (order)Ras-related protein Rab-11A,Ras-related protein Rab-11B
98IGZHaplorrhini (suborder)Ras-related protein Rab-11A,Ras-related protein Rab-11B
BUZ8TSimiiformes (infraorder)Ras-related protein Rab-11A,Ras-related protein Rab-11B
9EKMQCatarrhini (parvorder)Ras-related protein Rab-11B,Ras-related protein Rab-11A
7JM43Opisthokonta (clade)solute carrier family 39 (zinc transporter), member 1/2/3,Ras-related protein Rab-11B,Ras-related protein Rab-11A
H3JDVBilateria (clade)solute carrier family 39 (zinc transporter), member 1/2/3,Ras-related protein Rab-11B,Ras-related protein Rab-11A
9GDRWVertebrata (clade)Ras-related protein Rab-11B,Ras-related protein Rab-11A
FXFAIHominoidea (superfamily)Ras-related protein Rab-11A
5N29AHominidae (family)Ras-related protein Rab-11A
5XYSQHomininae (subfamily)Ras-related protein Rab-11A

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: