Domains within Mycobacterium bovis AF2122/97 protein IMDH_MYCBO (P65168)

Inosine-5'-monophosphate dehydrogenase

Alternative representations: 1 /

Protein length529 aa
Source databaseUniProt
Identifiers A0A1R3Y452, Q50715, X2BPI0, IMDH_MYCTO, P9WKI6, L0TCG3, P65167, IMDH_MYCTU, P9WKI7, A0A0E8U773_MYCTX, A0A0E8U773, A0A083VTE6_MYCBI, A0A083VTE6, A0A197J0C3_9MYCO, A0A197J0C3, A5U886_MYCTA, A5U886, I6X784_MYCTU, I6X784, A0A109SS60_9MYCO, A0A109SS60, A0A1S1B9F2_9MYCO, A0A1S1B9F2, F8M7J7_MYCA0, F8M7J7, G0TIS2_MYCCP, G0TIS2, A0A0H3MB68_MYCBP, A0A0H3MB68, A0A0T9F2A4_MYCTX, A0A0T9F2A4, A0A109SAL9_MYCBI, A0A109SAL9, A0A0H3LEK6_MYCTE, A0A0H3LEK6, IMDH_MYCBO, P65168

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

IMDH_MYCBO is shown as guaB2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for guaB2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 115862.BBG46_17770 in eggNOG.

OGTaxonomic classDescription
GJXKRMycobacterium tuberculosis complex (species group)IMP dehydrogenase [EC:1.1.1.205]
LCOG2905All organisms (root)arabinose-5-phosphate isomerase [EC:5.3.1.13],CBS domain-containing protein,IMP dehydrogenase [EC:1.1.1.205]
LCOG0516All organisms (root)IMP dehydrogenase [EC:1.1.1.205],GMP reductase [EC:1.7.1.7],DALR anticodon-binding domain-containing protein 3
COG0516Bacteria (superkingdom)IMP dehydrogenase [EC:1.1.1.205],GMP reductase [EC:1.7.1.7],chromosomal replication initiator protein
COG2905Bacteria (superkingdom)arabinose-5-phosphate isomerase [EC:5.3.1.13],CBS domain-containing protein,IMP dehydrogenase [EC:1.1.1.205]
6A4C7Actinobacteria (phylum)IMP dehydrogenase [EC:1.1.1.205],GMP reductase [EC:1.7.1.7]
F9IF8Actinomycetia (class)IMP dehydrogenase [EC:1.1.1.205]
EMU8SCorynebacteriales (order)IMP dehydrogenase [EC:1.1.1.205]
58B8SMycobacteriaceae (family)IMP dehydrogenase [EC:1.1.1.205]
HMM6NMycobacterium (genus)IMP dehydrogenase [EC:1.1.1.205]
EK6WRMycobacterium tuberculosis (species)IMP dehydrogenase [EC:1.1.1.205]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: