Domains within Homo sapiens protein RL24_HUMAN (P83731)

60S ribosomal protein L24

Alternative representations: 1 /

Protein length157 aa
Source databaseUniProt
Identifiers RL24_HUMAN, P83731, ENSP00000377640.3, ENSP00000377640, B2R4Y3, P38663, Q6IBS3, RL24_BOVIN, Q862I1, Q3T157, Q862I5, Q862V7, H2P9V3_PONAB, H2P9V3, RL24_FELCA, Q66WF5, RL24_MACFA, P61122, RL24_MOUSE, Q8BP67, Q58EA4, RL24_RAT, P83732, V9HW01_HUMAN, V9HW01, A0A0P6CX46_9CRUS, A0A0P6CX46, A0A2I3RK05_PANTR, A0A2I3RK05, G7MK26_MACMU, G7MK26, F2X267_AILME, F2X267, G3R7I4_GORGO, G3R7I4, A0A2J8T8Z3_PONAB, A0A2J8T8Z3, G1SE28_RABIT, G1SE28, A0A2K6L504_RHIBE, A0A2K6L504, A0A2K6C3J0_MACNE, A0A2K6C3J0, A0A2K5NCZ7_CERAT, A0A2K5NCZ7, A0A2K6RVF3_RHIRO, A0A2K6RVF3, A0A2K5CRQ4_AOTNA, A0A2K5CRQ4, A0A096MYF2_PAPAN, A0A096MYF2, A0A2K6EGE2_PROCO, A0A2K6EGE2, A0A212C3N0_CEREH, A0A212C3N0, A0A2K5K257_COLAP, A0A2K5K257, A0A2K6A3D4_MANLE, A0A2K6A3D4, F2Z5Q2_PIG, F2Z5Q2, A0A1U7UV49_TARSY, A0A1U7UV49, A0A2I3H3Q6_NOMLE, A0A2I3H3Q6, G5C020_HETGA, G5C020, A0A286XVX7_CAVPO, A0A286XVX7, A0A1S3FSU6_DIPOR, A0A1S3FSU6, A0A250YAH5_CASCN, A0A250YAH5, A0A1U7QUA9_MESAU, A0A1U7QUA9, A0A287DA37_ICTTR, A0A287DA37
Source gene ENSG00000114391
Alternative splicing RL24_HUMAN, C9JXB8_HUMAN, C9JNW5_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

RL24_HUMAN is shown as RPL24 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RPL24

Protein RL24_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05171Coronavirus disease - COVID-19

KEGG orthologous groups

KONameDescription
K02896RP-L24e, RPL24large subunit ribosomal protein L24e

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 34 PTMs annotated in this protein:

PTMCount
Ubiquitination14
Acetylation12
Phosphorylation7
Nitrosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein RPL24.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000377640 in eggNOG.

OGTaxonomic classDescription
LKOG1722All organisms (root)large subunit ribosomal protein L24e,membrane-associated progesterone receptor component
KOG1722Eukaryota (superkingdom)large subunit ribosomal protein L24e,membrane-associated progesterone receptor component
HU261Metazoa (kingdom)large subunit ribosomal protein L24e,membrane-associated progesterone receptor component
93Q8EChordata (phylum)large subunit ribosomal protein L24e
5QY84Sarcopterygii (superclass)large subunit ribosomal protein L24e
8ZAHDMammalia (class)large subunit ribosomal protein L24e
4RIR5Euarchontoglires (superorder)large subunit ribosomal protein L24e
50047Primates (order)large subunit ribosomal protein L24e
987MYHaplorrhini (suborder)large subunit ribosomal protein L24e
BVJ9VSimiiformes (infraorder)large subunit ribosomal protein L24e
9EFZRCatarrhini (parvorder)large subunit ribosomal protein L24e
H693VBilateria (clade)large subunit ribosomal protein L24e,membrane-associated progesterone receptor component
7KQPBOpisthokonta (clade)large subunit ribosomal protein L24e,membrane-associated progesterone receptor component
9GJ5TVertebrata (clade)large subunit ribosomal protein L24e
FXB58Hominoidea (superfamily)large subunit ribosomal protein L24e
5N1RDHominidae (family)large subunit ribosomal protein L24e
5Y6Z1Homininae (subfamily)large subunit ribosomal protein L24e

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: