Domains within Schizosaccharomyces pombe 972h- protein RHP9_SCHPO (P87074)

DNA repair protein crb2

Alternative representations: 1 /

Protein length778 aa
Source databaseUniProt
Identifiers Q09754, RHP9_SCHPO, P87074

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

RHP9_SCHPO is shown as crb2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for crb2

Protein RHP9_SCHPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04111Cell cycle - yeast
map04621NOD-like receptor signaling pathway

KEGG orthologous groups

KONameDescription
K06661RAD9DNA repair protein RAD9
K20915TP53BP1, P202tumor suppressor p53-binding protein 1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 7 PTMs annotated in this protein:

PTMCount
Phosphorylation7

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein rhp9.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284812.P87074 in eggNOG.

OGTaxonomic classDescription
FS7ITDikarya (subkingdom)DNA repair protein RAD9,glycopeptidolipid biosynthesis protein
LKOG3548All organisms (root)tumor suppressor p53-binding protein 1,DNA repair protein RAD9,glycopeptidolipid biosynthesis protein
KOG3548Eukaryota (superkingdom)tumor suppressor p53-binding protein 1,DNA repair protein RAD9,glycopeptidolipid biosynthesis protein
BMKS3Fungi (kingdom)DNA repair protein RAD9,glycopeptidolipid biosynthesis protein
9TD0TAscomycota (phylum)DNA repair protein RAD9,glycopeptidolipid biosynthesis protein
DVET3Taphrinomycotina (subphylum)Rad9_Rad53_bind,BRCT,Tudor_3
7KKAROpisthokonta (clade)tumor suppressor p53-binding protein 1,DNA repair protein RAD9,glycopeptidolipid biosynthesis protein
CE3E2Schizosaccharomyces (genus)Tudor_3,BRCT

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: