Domains within Mus musculus protein CXAR_MOUSE (P97792)

Coxsackievirus and adenovirus receptor homolog

Alternative representations: 1 /

Protein length365 aa
Source databaseUniProt
Identifiers CXAR_MOUSE, P97792, ENSMUSP00000023572.7, ENSMUSP00000023572, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8
Source gene ENSMUSG00000022865
Alternative splicing CXAR_MOUSE, P97792-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CXAR_MOUSE is shown as Cxadr in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Cxadr

Protein CXAR_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05416Viral myocarditis
map04210Apoptosis

KEGG orthologous groups

KONameDescription
K06788CXADR, CARcoxsackievirus and adenovirus receptor
K04397CASP7caspase 7 [EC:3.4.22.60]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 34 PTMs annotated in this protein:

PTMCount
Phosphorylation19
Acetylation7
Ubiquitination3
Palmitoylation2
Oxidation2
N-linked glycosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Cxadr.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000023572 in eggNOG.

OGTaxonomic classDescription
LKOG3573All organisms (root)caspase 7 [EC:3.4.22.60],caspase 8 [EC:3.4.22.61],caspase 3 [EC:3.4.22.56]
KOG3573Eukaryota (superkingdom)caspase 7 [EC:3.4.22.60],caspase 8 [EC:3.4.22.61],caspase 3 [EC:3.4.22.56]
HUZERMetazoa (kingdom)coxsackievirus and adenovirus receptor
93EG9Chordata (phylum)coxsackievirus and adenovirus receptor
5QBF3Sarcopterygii (superclass)coxsackievirus and adenovirus receptor
8ZMICMammalia (class)coxsackievirus and adenovirus receptor
4RSCWEuarchontoglires (superorder)coxsackievirus and adenovirus receptor
AIG6GRodentia (order)coxsackievirus and adenovirus receptor
8DFQ7Myomorpha (suborder)coxsackievirus and adenovirus receptor
9GFF4Vertebrata (clade)coxsackievirus and adenovirus receptor
H4UQBBilateria (clade)coxsackievirus and adenovirus receptor
7H879Opisthokonta (clade)coxsackievirus and adenovirus receptor
CQBV0Muridae (family)coxsackievirus and adenovirus receptor
AE88WMurinae (subfamily)coxsackievirus and adenovirus receptor
5PYDRMus (genus)coxsackievirus and adenovirus receptor
HECE2Mus (subgenus)coxsackievirus and adenovirus receptor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: