Domains within Mus musculus protein IHH_MOUSE (P97812)

Indian hedgehog protein

Alternative representations: 1 /

Protein length411 aa
Source databaseUniProt
Identifiers IHH_MOUSE, P97812, ENSMUSP00000128056.2, ENSMUSP00000128056, Q61724, Q80XI9_MOUSE, Q80XI9, F6RLD8_MOUSE, F6RLD8
Source gene ENSMUSG00000006538

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

IHH_MOUSE is shown as Ihh in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ihh

Protein IHH_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04340Hedgehog signaling pathway

KEGG orthologous groups

KONameDescription
K11989IHHindian hedgehog

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000128056 in eggNOG.

OGTaxonomic classDescription
LKOG3638All organisms (root)indian hedgehog,desert hedgehog,sonic hedgehog
KOG3638Eukaryota (superkingdom)indian hedgehog,desert hedgehog,sonic hedgehog
HW0BBMetazoa (kingdom)indian hedgehog,sonic hedgehog,desert hedgehog
93PSPChordata (phylum)indian hedgehog,sonic hedgehog,desert hedgehog
5QGV5Sarcopterygii (superclass)indian hedgehog,sonic hedgehog,desert hedgehog
8ZGDPMammalia (class)indian hedgehog,sonic hedgehog
4R9SREuarchontoglires (superorder)indian hedgehog
AIAMWRodentia (order)indian hedgehog
8DD2MMyomorpha (suborder)indian hedgehog
H3TQBBilateria (clade)indian hedgehog,sonic hedgehog,desert hedgehog
7GB6YOpisthokonta (clade)indian hedgehog,sonic hedgehog,desert hedgehog
9FF5WVertebrata (clade)indian hedgehog,sonic hedgehog,desert hedgehog
CQBDUMuridae (family)indian hedgehog
AE9KXMurinae (subfamily)indian hedgehog
5PS2NMus (genus)indian hedgehog
HE5U2Mus (subgenus)indian hedgehog

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: