Domains within Rattus norvegicus protein RGS1_RAT (P97844)

Regulator of G-protein signaling 1

Alternative representations: 1 /

Protein length209 aa
Source databaseUniProt
Identifiers RGS1_RAT, P97844, ENSRNOP00000005251.5, ENSRNOP00000005251, A0A0H2UHC4, Q4KM99, P97844-2
Source gene ENSRNOG00000003895

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

RGS1_RAT is shown as Rgs1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Rgs1

Protein RGS1_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04360Axon guidance
map04921Oxytocin signaling pathway
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K16449RGSregulator of G-protein signaling

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000005251 in eggNOG.

OGTaxonomic classDescription
LKOG3589All organisms (root)regulator of G-protein signaling,axin 1,regulator of G-protein signaling 2
KOG3589Eukaryota (superkingdom)regulator of G-protein signaling,axin 1,regulator of G-protein signaling 2
HVJ6MMetazoa (kingdom)regulator of G-protein signaling,regulator of G-protein signalling 3,regulator of G-protein signaling 2
94CM0Chordata (phylum)regulator of G-protein signaling
5QMVQSarcopterygii (superclass)regulator of G-protein signaling
8Z8UWMammalia (class)regulator of G-protein signaling
4RD3DEuarchontoglires (superorder)regulator of G-protein signaling
AI7U5Rodentia (order)regulator of G-protein signaling
8DAPNMyomorpha (suborder)regulator of G-protein signaling
7GRC5Opisthokonta (clade)regulator of G-protein signaling,regulator of G-protein signaling 2,regulator of G-protein signaling 9
9GQYAVertebrata (clade)regulator of G-protein signaling
H5CK5Bilateria (clade)regulator of G-protein signaling
CQ6IKMuridae (family)regulator of G-protein signaling
ADX7KMurinae (subfamily)regulator of G-protein signaling

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: