Domains within Mus musculus protein TYY1_MOUSE (Q00899)

Transcriptional repressor protein YY1

Alternative representations: 1 /

Protein length414 aa
Source databaseUniProt
Identifiers TYY1_MOUSE, Q00899, ENSMUSP00000021692.7, ENSMUSP00000021692
Source gene ENSMUSG00000021264

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

TYY1_MOUSE is shown as Yy1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Yy1

Protein TYY1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04141Protein processing in endoplasmic reticulum
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein
K09201YYtranscription factor YY

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 26 PTMs annotated in this protein:

PTMCount
Phosphorylation14
Acetylation6
Ubiquitination5
SUMOylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Yy1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000021692 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HSRYXMetazoa (kingdom)transcription factor YY,zinc finger protein 42,S2P endopeptidase [EC:3.4.24.85]
94D98Chordata (phylum)transcription factor YY,zinc finger protein 42,S2P endopeptidase [EC:3.4.24.85]
5R9JESarcopterygii (superclass)transcription factor YY,zinc finger protein 42,S2P endopeptidase [EC:3.4.24.85]
8ZC4SMammalia (class)transcription factor YY,zinc finger protein 42,S2P endopeptidase [EC:3.4.24.85]
4RE2CEuarchontoglires (superorder)zinc finger protein 42,transcription factor YY
AIDTJRodentia (order)transcription factor YY
8DGV2Myomorpha (suborder)transcription factor YY
9FK0QVertebrata (clade)transcription factor YY,zinc finger protein 42,S2P endopeptidase [EC:3.4.24.85]
H6RBXBilateria (clade)transcription factor YY,zinc finger protein 42,S2P endopeptidase [EC:3.4.24.85]
7MTDYOpisthokonta (clade)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
CQG7AMuridae (family)transcription factor YY
AE7JBMurinae (subfamily)transcription factor YY
5PVDXMus (genus)transcription factor YY
HEAQBMus (subgenus)transcription factor YY

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: