Domains within Mus musculus protein ASIP_MOUSE (Q03288)

Agouti-signaling protein

Alternative representations: 1 /

Protein length131 aa
Source databaseUniProt
Identifiers ASIP_MOUSE, Q03288, ENSMUSP00000105319.1, ENSMUSP00000105319, ENSMUSP00000029123.2, ENSMUSP00000029123, A2ALT3, Q80ST0, A2ALT2_MOUSE, A2ALT2, A2ALT1_MOUSE, A2ALT1
Source gene ENSMUSG00000027596
Alternative splicing ENSMUSP00000122261.1, ASIP_MOUSE, ENSMUSP00000121072.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

ASIP_MOUSE is shown as a in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

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Protein ASIP_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04916Melanogenesis

KEGG orthologous groups

KONameDescription
K08725ASIPagouti signaling protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
Methylation2
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Asip.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000029123 in eggNOG.

OGTaxonomic classDescription
730H0All organisms (root)agouti signaling protein
5JIQ3Eukaryota (superkingdom)agouti signaling protein
HW4HFMetazoa (kingdom)agouti signaling protein
93JXIChordata (phylum)agouti signaling protein
5QRF8Sarcopterygii (superclass)agouti signaling protein
8ZF73Mammalia (class)agouti signaling protein
4R2NPEuarchontoglires (superorder)agouti signaling protein
AI48XRodentia (order)agouti signaling protein
8DNCSMyomorpha (suborder)agouti signaling protein
H591YBilateria (clade)agouti signaling protein
9GBPCVertebrata (clade)agouti signaling protein
7HQASOpisthokonta (clade)agouti signaling protein
CPZD9Muridae (family)agouti signaling protein
AE39KMurinae (subfamily)agouti signaling protein
5PM8NMus (genus)agouti signaling protein
HEDURMus (subgenus)agouti signaling protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: