Domains within Saccharomyces cerevisiae S288C protein HRD3_YEAST (Q05787)

ERAD-associated E3 ubiquitin-protein ligase component HRD3

Alternative representations: 1 /

Protein length833 aa
Source databaseUniProt
Identifiers D6VYK8, N1P6T7_YEASC, N1P6T7, HRD3_YEAST, Q05787

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

HRD3_YEAST is shown as HRD3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HRD3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
N-linked glycosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_122470.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YLR207W in eggNOG.

OGTaxonomic classDescription
LCOG0790All organisms (root)uncharacterized protein,SEL1 protein,cytochrome c oxidase assembly factor 7
FTB4ZDikarya (subkingdom)SEL1 protein,ERAD-associated E3 ubiquitin-protein ligase component HRD3,uncharacterized protein
KOG1550Eukaryota (superkingdom)SEL1 protein,uncharacterized protein,ERAD-associated E3 ubiquitin-protein ligase component HRD3
BNVEZFungi (kingdom)SEL1 protein,ERAD-associated E3 ubiquitin-protein ligase component HRD3,uncharacterized protein
9TI8KAscomycota (phylum)SEL1 protein,ERAD-associated E3 ubiquitin-protein ligase component HRD3
91JY0Saccharomycetales (order)ERAD-associated E3 ubiquitin-protein ligase component HRD3,SEL1 protein
7N4QFOpisthokonta (clade)SEL1 protein,ERAD-associated E3 ubiquitin-protein ligase component HRD3,cystinosin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: