Domains within Rattus norvegicus protein ANXA2_RAT (Q07936)

Annexin A2

Alternative representations: 1 /

Protein length339 aa
Source databaseUniProt
Identifiers ANXA2_RAT, Q07936, ENSRNOP00000038428.5, ENSRNOP00000038428
Source gene ENSRNOG00000010362

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ANXA2_RAT is shown as Anxa2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Anxa2

Protein ANXA2_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05132Salmonella infection
map05014Amyotrophic lateral sclerosis

KEGG orthologous groups

KONameDescription
K17092ANXA2annexin A2
K17098ANNATannexin D

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000038428 in eggNOG.

OGTaxonomic classDescription
LKOG0819All organisms (root)annexin D,annexin A7/11,annexin A2
KOG0819Eukaryota (superkingdom)annexin D,annexin A7/11,annexin A2
HVEW0Metazoa (kingdom)annexin A1,annexin A2
94RVWChordata (phylum)annexin A1,annexin A2
5QHQ3Sarcopterygii (superclass)annexin A2
8Z05UMammalia (class)annexin A2
4R1UZEuarchontoglires (superorder)annexin A2
AI315Rodentia (order)annexin A2
8DKN9Myomorpha (suborder)annexin A2
7MQM5Opisthokonta (clade)annexin A1,annexin A2
H5GSZBilateria (clade)annexin A1,annexin A2
9FHPQVertebrata (clade)annexin A1,annexin A2
CQ276Muridae (family)annexin A2
ADVXUMurinae (subfamily)annexin A2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: