Domains within Alkalilimnicola ehrlichii MLHE-1 protein CCA_ALKEH (Q0ACP8)

Multifunctional CCA protein

Alternative representations: 1 /

Protein length413 aa
Source databaseUniProt
Identifiers CCA_ALKEH, Q0ACP8

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CCA_ALKEH is shown as Mlg_0030 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Mlg_0030

Protein CCA_ALKEH is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03018RNA degradation

KEGG orthologous groups

KONameDescription
K00974ccatRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
K00970pcnBpoly(A) polymerase [EC:2.7.7.19]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 187272.Mlg_0030 in eggNOG.

OGTaxonomic classDescription
LCOG0617All organisms (root)tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-],poly(A) polymerase [EC:2.7.7.19],lincosamide nucleotidyltransferase A/C/D/E
COG0617Bacteria (superkingdom)poly(A) polymerase [EC:2.7.7.19],tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-],protein archease
60JUDProteobacteria (phylum)tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-],poly(A) polymerase [EC:2.7.7.19]
ERK7YGammaproteobacteria (class)tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
CN6AZChromatiales (order)tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
83JQDEctothiorhodospiraceae (family)tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: