Domains within Frankia alni ACN14a protein Q0RKW8_FRAAA (Q0RKW8)

Putative multi-domain beta-ketoacyl synthase

Alternative representations: 1 /

Protein length2481 aa
Source databaseUniProt
Identifiers Q0RKW8_FRAAA, Q0RKW8

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

Q0RKW8_FRAAA is shown as FRAAL3193 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for FRAAL3193

Protein Q0RKW8_FRAAA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map01059Biosynthesis of enediyne antibiotics iPath3
map01053Biosynthesis of siderophore group nonribosomal peptides iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K00665FASNfatty acid synthase, animal type [EC:2.3.1.85] iPath3
K12437pks13polyketide synthase 13
K02078acpP, acpMacyl carrier protein
K12434pks7polyketide synthase 7
K12444ppsEphthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 326424.FRAAL3193 in eggNOG.

OGTaxonomic classDescription
LCOG0236All organisms (root)acyl carrier protein,NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein,D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
LCOG3321All organisms (root)fatty acid synthase, animal type [EC:2.3.1.85],chalcone synthase [EC:2.3.1.74],phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]
COG0236Bacteria (superkingdom)acyl carrier protein,D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13],polyketide synthase 13
COG3321Bacteria (superkingdom)phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292],polyketide synthase 13,phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase C [EC:2.3.1.292]
6A302Actinobacteria (phylum)polyketide synthase 13,mycobactin phenyloxazoline synthetase,phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]
FA04HActinomycetia (class)polyketide synthase 13,mycobactin phenyloxazoline synthetase,phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]
8Y2TBFrankiales (order)phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292],polyketide synthase 7,6-methylsalicylic acid synthase [EC:2.3.1.165]
AMTBPFrankiaceae (family)PP-binding,ketoacyl-synt,Ketoacyl-synt_C
8E7I2Frankia (genus)PP-binding,ketoacyl-synt,Ketoacyl-synt_C

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: