Domains within Parastagonospora nodorum SN15 protein H2A_PHANO (Q0U1A1)

Histone H2A

Alternative representations: 1 /

Protein length134 aa
Source databaseUniProt
Identifiers M2T2C8_COCSN, M2T2C8, W7A0Y9_COCMI, W7A0Y9, A0A178DS08_9PLEO, A0A178DS08, E5A331_LEPMJ, E5A331, W6YUW8_COCCA, W6YUW8, W7EVJ3_COCVI, W7EVJ3, B2VXN4_PYRTR, B2VXN4, N4XEV1_COCH4, N4XEV1, A0A177DXN0_ALTAL, A0A177DXN0, A0A177BXY2_9PLEO, A0A177BXY2, M2UE52_COCH5, M2UE52, R0KKQ7_SETT2, R0KKQ7, A0A0L1I2W1_9PLEO, A0A0L1I2W1, E3S4K1_PYRTT, E3S4K1, A0A178ARI0_9PLEO, A0A178ARI0, H2A_PHANO, Q0U1A1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

H2A_PHANO is shown as HTA1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HTA1

Protein H2A_PHANO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04217Necroptosis
map05034Alcoholism

KEGG orthologous groups

KONameDescription
K11251H2Ahistone H2A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 321614.Q0U1A1 in eggNOG.

OGTaxonomic classDescription
7553CAll organisms (root)histone H2A,pleckstrin homology domain-containing family A member 1/2,histone H1/5
FT6HADikarya (subkingdom)histone H2A
KOG1756Eukaryota (superkingdom)histone H2A,pleckstrin homology domain-containing family A member 1/2,histone H1/5
BP0DGFungi (kingdom)histone H2A
9UNR7Ascomycota (phylum)histone H2A
C44IKPezizomycotina (subphylum)histone H2A
HEWY1Dothideomycetes (class)histone H2A
EAK12Pleosporales (order)histone H2A
AUZ9NPleosporineae (suborder)histone H2A
7GT9HOpisthokonta (clade)histone H2A,histone H1/5,mature T-cell proliferation-1 type B1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: