Domains within Schizosaccharomyces pombe 972h- protein ABC2_SCHPO (Q10185)

ATP-binding cassette transporter abc2

Alternative representations: 1 /

Protein length1478 aa
Source databaseUniProt
Identifiers P78928, ABC2_SCHPO, Q10185

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ABC2_SCHPO is shown as abc2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for abc2

Protein ABC2_SCHPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02010ABC transporters
map04977Vitamin digestion and absorption

KEGG orthologous groups

KONameDescription
K06147ABCB-BACATP-binding cassette, subfamily B, bacterial
K05665ABCC1ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284812.Q10185 in eggNOG.

OGTaxonomic classDescription
FR0T7Dikarya (subkingdom)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
LCOG1132All organisms (root)ATP-binding cassette, subfamily B, multidrug efflux pump,ATP-binding cassette, subfamily B, bacterial,ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
KOG0054Eukaryota (superkingdom)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3],ATP-binding cassette, subfamily C (CFTR/MRP), member 4,ATP-binding cassette, subfamily C (CFTR/MRP), member 2
BKVDSFungi (kingdom)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
9UW72Ascomycota (phylum)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
DVGD4Taphrinomycotina (subphylum)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
7I0G9Opisthokonta (clade)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3],ATP-binding cassette, subfamily C (CFTR/MRP), member 4,ATP-binding cassette, subfamily C (CFTR/MRP), member 5
CE4XTSchizosaccharomyces (genus)ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: