Domains within Aedes aegypti protein Q16GJ6_AEDAE (Q16GJ6)

AAEL014356-PA

Alternative representations: 1 /

Protein length856 aa
Source databaseUniProt
Identifiers Q16GJ6_AEDAE, Q16GJ6

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

Q16GJ6_AEDAE is shown as CTLSE2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CTLSE2

Protein Q16GJ6_AEDAE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04145Phagosome
map04979Cholesterol metabolism

KEGG orthologous groups

KONameDescription
K17495CSMDCUB and sushi domain-containing protein
K06560MRC, CD206, CD280mannose receptor, C type

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7159.Q16GJ6 in eggNOG.

OGTaxonomic classDescription
EJCFPEndopterygota (cohort)Lectin_C,Sushi,DUF4817
LKOG4297All organisms (root)mannose receptor, C type,CUB and sushi domain-containing protein,E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
KOG4297Eukaryota (superkingdom)mannose receptor, C type,CUB and sushi domain-containing protein,E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
HV6G4Metazoa (kingdom)CUB and sushi domain-containing protein
HIK0HArthropoda (phylum)Sushi,Lectin_C,F5_F8_type_C
868Q3Hexapoda (subphylum)Sushi,Lectin_C,DUF4817
AGTZUNeoptera (infraclass)Sushi,Lectin_C,DUF4817
ANJWBDiptera (order)Sushi,Lectin_C
G9PH5Culicomorpha (infraorder)Sushi,Lectin_C
H3TFXBilateria (clade)CUB and sushi domain-containing protein
7IFIBOpisthokonta (clade)CUB and sushi domain-containing protein,apolipoprotein(a) [EC:3.4.21.-]
9KZ39Culicidae (family)Sushi,Lectin_C
DA8T7Culicinae (subfamily)Lectin_C,Sushi

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: