Domains within Aedes aegypti protein Q16UH5_AEDAE (Q16UH5)

Proteasome subunit alpha type

Alternative representations: 1 /

Protein length246 aa
Source databaseUniProt
Identifiers Q16UH5_AEDAE, Q16UH5

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

Q16UH5_AEDAE is shown as AAEL009898 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for AAEL009898

Protein Q16UH5_AEDAE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05016Huntington disease
map03050Proteasome

KEGG orthologous groups

KONameDescription
K02730PSMA620S proteasome subunit alpha 1 [EC:3.4.25.1]
K03433psmB, prcBproteasome beta subunit [EC:3.4.25.1]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 13 PTMs annotated in this protein:

PTMCount
Phosphorylation6
Acetylation3
Nitrosylation1
Ubiquitination1
O-linked glycosylation1
O-GlcNAc glycosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AAEL009898.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7159.Q16UH5 in eggNOG.

OGTaxonomic classDescription
EJ213Endopterygota (cohort)20S proteasome subunit alpha 1 [EC:3.4.25.1]
LCOG0638All organisms (root)proteasome beta subunit [EC:3.4.25.1],20S proteasome subunit beta 2 [EC:3.4.25.1],20S proteasome subunit alpha 4 [EC:3.4.25.1]
KOG0182Eukaryota (superkingdom)20S proteasome subunit alpha 1 [EC:3.4.25.1]
HV9XHMetazoa (kingdom)20S proteasome subunit alpha 1 [EC:3.4.25.1]
HIJ9IArthropoda (phylum)20S proteasome subunit alpha 1 [EC:3.4.25.1]
85FI2Hexapoda (subphylum)20S proteasome subunit alpha 1 [EC:3.4.25.1]
AH2ARNeoptera (infraclass)20S proteasome subunit alpha 1 [EC:3.4.25.1]
ANQ1UDiptera (order)20S proteasome subunit alpha 1 [EC:3.4.25.1]
G9K3ZCulicomorpha (infraorder)20S proteasome subunit alpha 1 [EC:3.4.25.1]
H58VSBilateria (clade)20S proteasome subunit alpha 1 [EC:3.4.25.1]
7MMAGOpisthokonta (clade)20S proteasome subunit alpha 1 [EC:3.4.25.1]
9M902Culicidae (family)20S proteasome subunit alpha 1 [EC:3.4.25.1]
DAACRCulicinae (subfamily)20S proteasome subunit alpha 1 [EC:3.4.25.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: