Domains within Caenorhabditis elegans protein PIN2_CAEEL (Q19157)

LIM domain-containing protein pin-2

Alternative representations: 1 /

Protein length330 aa
Source databaseUniProt
Identifiers PIN2_CAEEL, Q19157, F07C6.1A, H9G2V0, H9G2V1, Q19157-2
Source gene WBGene00004030
Alternative splicing PIN2_CAEEL, F07C6.1b

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

PIN2_CAEEL is shown as pin-2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for pin-2

Protein PIN2_CAEEL is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04360Axon guidance

KEGG orthologous groups

KONameDescription
K23354LIMS1_2, PINCH1_2LIM and senescent cell antigen-like-containing domain protein 1/2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 6239.F07C6.1a.1 in eggNOG.

OGTaxonomic classDescription
LKOG2272All organisms (root)LIM and senescent cell antigen-like-containing domain protein 1/2,actin-binding LIM protein
KOG2272Eukaryota (superkingdom)LIM and senescent cell antigen-like-containing domain protein 1/2,actin-binding LIM protein
HUPMXMetazoa (kingdom)LIM and senescent cell antigen-like-containing domain protein 1/2
8BCDSNematoda (phylum)LIM and senescent cell antigen-like-containing domain protein 1/2
HDG0WChromadorea (class)LIM and senescent cell antigen-like-containing domain protein 1/2
6DVGGRhabditida (order)LIM and senescent cell antigen-like-containing domain protein 1/2
8Q2KKRhabditina (suborder)LIM and senescent cell antigen-like-containing domain protein 1/2
7MGKIOpisthokonta (clade)LIM and senescent cell antigen-like-containing domain protein 1/2
H4CD6Bilateria (clade)LIM and senescent cell antigen-like-containing domain protein 1/2
AYKQKRhabditidae (family)LIM and senescent cell antigen-like-containing domain protein 1/2
BT3UVCaenorhabditis (genus)LIM and senescent cell antigen-like-containing domain protein 1/2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: