Domains within Mus musculus protein TRI72_MOUSE (Q1XH17)

Tripartite motif-containing protein 72

Alternative representations: 1 /

Protein length477 aa
Source databaseUniProt
Identifiers TRI72_MOUSE, Q1XH17, ENSMUSP00000101855.1, ENSMUSP00000101855, ENSMUSP00000079832.4, ENSMUSP00000079832, B2RWH7, Q6NX76
Source gene ENSMUSG00000042828

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

TRI72_MOUSE is shown as Trim72 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Trim72

Protein TRI72_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04361Axon regeneration
map04120Ubiquitin mediated proteolysis

KEGG orthologous groups

KONameDescription
K06712BTN, CD277butyrophilin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 12 PTMs annotated in this protein:

PTMCount
Phosphorylation6
Nitrosylation4
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Trim72.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000101855 in eggNOG.

OGTaxonomic classDescription
LKOG2177All organisms (root)butyrophilin,tripartite motif-containing protein 2/3,deltex [EC:2.3.2.27]
KOG2177Eukaryota (superkingdom)butyrophilin,tripartite motif-containing protein 2/3,deltex [EC:2.3.2.27]
HVPGDMetazoa (kingdom)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 2/3
94EAXChordata (phylum)tripartite motif-containing protein 50/73/74,tripartite motif-containing protein 72
5QXQ9Sarcopterygii (superclass)tripartite motif-containing protein 72
8YUEIMammalia (class)tripartite motif-containing protein 72
4RJABEuarchontoglires (superorder)tripartite motif-containing protein 72
AI9D3Rodentia (order)tripartite motif-containing protein 72
8D6DMMyomorpha (suborder)tripartite motif-containing protein 72
7KUB7Opisthokonta (clade)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 2/3
9GRHHVertebrata (clade)tripartite motif-containing protein 50/73/74,tripartite motif-containing protein 72
H6GQGBilateria (clade)butyrophilin,tripartite motif-containing protein 35,tripartite motif-containing protein 2/3
CQAUSMuridae (family)tripartite motif-containing protein 72
ADZ39Murinae (subfamily)tripartite motif-containing protein 72
5PNZZMus (genus)tripartite motif-containing protein 72
HE2T8Mus (subgenus)tripartite motif-containing protein 72

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: