Domains within Mus musculus protein BZW2_MOUSE (Q91VK1)

Basic leucine zipper and W2 domain-containing protein 2

Alternative representations: 1 /

Protein length419 aa
Source databaseUniProt
Identifiers BZW2_MOUSE, Q91VK1, ENSMUSP00000020856.4, ENSMUSP00000020856, Q9D0N4, BZW2_MUSMM, Q2L4X1, Q3TRM2_MOUSE, Q3TRM2, A0A1Y7VJ43_MOUSE, A0A1Y7VJ43, A0A1Y7VIU9_MOUSE, A0A1Y7VIU9
Source gene ENSMUSG00000020547
Alternative splicing BZW2_MOUSE, A0A1Y7VKZ4_MOUSE, ENSMUSP00000152263.1, ENSMUSP00000152148.1, ENSMUSP00000152800.1, ENSMUSP00000152765.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

BZW2_MOUSE is shown as Bzw2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Bzw2

Protein BZW2_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04111Cell cycle - yeast

KEGG orthologous groups

KONameDescription
K06670SCC1, MCD1, RAD21cohesin complex subunit SCC1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 6 PTMs annotated in this protein:

PTMCount
Phosphorylation4
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Bzw2.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000020856 in eggNOG.

OGTaxonomic classDescription
LKOG2297All organisms (root)cohesin complex subunit SCC1
KOG2297Eukaryota (superkingdom)cohesin complex subunit SCC1
HUG92Metazoa (kingdom)W2,Myb_DNA-bind_5,Abhydro_lipase
945R8Chordata (phylum)W2,Tetraspanin
5QJJ6Sarcopterygii (superclass)W2
8Z01ZMammalia (class)W2
4RNA8Euarchontoglires (superorder)W2
AIFIURodentia (order)W2
8DMP7Myomorpha (suborder)W2
9G9STVertebrata (clade)W2,Tetraspanin
7N2GBOpisthokonta (clade)W2,Myb_DNA-bind_5,SH3_1
H3Y7XBilateria (clade)W2,Myb_DNA-bind_5,Abhydro_lipase
CQ6BWMuridae (family)W2
ADWD9Murinae (subfamily)W2
5PQP7Mus (genus)W2
HE7X3Mus (subgenus)W2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: