Domains within Homo sapiens protein BSH_HUMAN (Q3C1V8)

Brain-specific homeobox protein homolog

Alternative representations: 1 /

Protein length233 aa
Source databaseUniProt
Identifiers BSH_HUMAN, Q3C1V8, ENSP00000344285.2, ENSP00000344285
Source gene ENSG00000188909

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

BSH_HUMAN is shown as BSX in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BSX

Protein BSH_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05205Proteoglycans in cancer

KEGG orthologous groups

KONameDescription
K24874BSXbrain-specific homeobox protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000344285 in eggNOG.

OGTaxonomic classDescription
LKOG0491All organisms (root)brain-specific homeobox protein,homeobox protein Nanog,homeo domain only family, other
KOG0491Eukaryota (superkingdom)brain-specific homeobox protein,homeobox protein Nanog,homeo domain only family, other
HV5H5Metazoa (kingdom)brain-specific homeobox protein
94U8AChordata (phylum)brain-specific homeobox protein
5R2FSSarcopterygii (superclass)brain-specific homeobox protein
8ZMTYMammalia (class)brain-specific homeobox protein
4R9SKEuarchontoglires (superorder)brain-specific homeobox protein
4ZPBFPrimates (order)brain-specific homeobox protein
98QG9Haplorrhini (suborder)brain-specific homeobox protein
BV5ZNSimiiformes (infraorder)brain-specific homeobox protein
9EHG5Catarrhini (parvorder)brain-specific homeobox protein
7J5FAOpisthokonta (clade)brain-specific homeobox protein
9G53MVertebrata (clade)brain-specific homeobox protein
H41ZZBilateria (clade)brain-specific homeobox protein
FX463Hominoidea (superfamily)brain-specific homeobox protein
5MYKBHominidae (family)brain-specific homeobox protein
5XXZYHomininae (subfamily)brain-specific homeobox protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: