Domains within Mus musculus protein CYR61_MOUSE (P18406)

Protein CYR61

Alternative representations: 1 /

Protein length379 aa
Source databaseUniProt
Identifiers CYR61_MOUSE, P18406, ENSMUSP00000029846.3, ENSMUSP00000029846, Q3TX21_MOUSE, Q3TX21
Source gene ENSMUSG00000028195

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

CYR61_MOUSE is shown as Ccn1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ccn1

Protein CYR61_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04371Apelin signaling pathway

KEGG orthologous groups

KONameDescription
K06829CYR61, CCN1, IGFBP10insulin-like growth factor-binding protein 10
K06827CTGF, CCN2, IGFBP8connective tissue growth factor (insulin-like growth factor-binding protein 8)

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000029846 in eggNOG.

OGTaxonomic classDescription
76T4NAll organisms (root)insulin-like growth factor-binding protein 10,connective tissue growth factor (insulin-like growth factor-binding protein 8),CCN family member 4
5EE0REukaryota (superkingdom)insulin-like growth factor-binding protein 10,connective tissue growth factor (insulin-like growth factor-binding protein 8),CCN family member 4
HSU27Metazoa (kingdom)connective tissue growth factor (insulin-like growth factor-binding protein 8),insulin-like growth factor-binding protein 10,CCN family member 4
93ZC8Chordata (phylum)insulin-like growth factor-binding protein 10
5QXZ8Sarcopterygii (superclass)insulin-like growth factor-binding protein 10
8ZFR2Mammalia (class)insulin-like growth factor-binding protein 10
4R56CEuarchontoglires (superorder)insulin-like growth factor-binding protein 10
AI238Rodentia (order)insulin-like growth factor-binding protein 10
8DK2NMyomorpha (suborder)insulin-like growth factor-binding protein 10
H4AZSBilateria (clade)connective tissue growth factor (insulin-like growth factor-binding protein 8),insulin-like growth factor-binding protein 10,CCN family member 4
7GN2NOpisthokonta (clade)connective tissue growth factor (insulin-like growth factor-binding protein 8),insulin-like growth factor-binding protein 10,CCN family member 4
9FVUWVertebrata (clade)insulin-like growth factor-binding protein 10
CQEKBMuridae (family)insulin-like growth factor-binding protein 10
AE9UVMurinae (subfamily)insulin-like growth factor-binding protein 10
5PWVBMus (genus)insulin-like growth factor-binding protein 10
HEEFXMus (subgenus)insulin-like growth factor-binding protein 10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: