Domains within Aspergillus fumigatus Af293 protein UBC2_ASPFU (Q4WLA7)

Ubiquitin-conjugating enzyme E2 2

Alternative representations: 1 /

Protein length151 aa
Source databaseUniProt
Identifiers G7XM94, A0A0L1JDE3_ASPNO, A0A0L1JDE3, A0A229XEZ4_9EURO, A0A229XEZ4, A0A100IPV1_ASPNG, A0A100IPV1, A0A2I2EU04_9EURO, A0A2I2EU04, A0A0J5Q477_ASPFM, A0A0J5Q477, A0A1R3S0Y6_ASPC5, A0A1R3S0Y6, A0A146F9X9_9EURO, A0A146F9X9, G7XM94_ASPKW, Q0CZF3_ASPTN, Q0CZF3, G3YG56_ASPNA, G3YG56, A0A0K8LKQ5_9EURO, A0A0K8LKQ5, A0A1L9UNG0_9EURO, A0A1L9UNG0, A0A1L9WPQ9_ASPAC, A0A1L9WPQ9, A0A229WJ66_ASPFM, A0A229WJ66, A0A1M3T3F0_9EURO, A0A1M3T3F0, A0A1F7ZWP4_9EURO, A0A1F7ZWP4, I7ZNI5_ASPO3, I7ZNI5, A0A2G7G3Q1_9EURO, A0A2G7G3Q1, A0A1L9NQB9_ASPTU, A0A1L9NQB9, B0XMC0_ASPFC, B0XMC0, B8NXL1_ASPFN, B8NXL1, A0A0D9MXB6_ASPFA, A0A0D9MXB6, A1DPD2_NEOFI, A1DPD2, A0A0S7DE18_9EURO, A0A0S7DE18, A2QLG6_ASPNC, A2QLG6, A0A2I1CBB9_9EURO, A0A2I1CBB9, A0A231MLS4_9EURO, A0A231MLS4, Q2TY35_ASPOR, Q2TY35, UBC2_ASPFU, Q4WLA7

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

UBC2_ASPFU is shown as ubc2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ubc2

Protein UBC2_ASPFU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis

KEGG orthologous groups

KONameDescription
K06689UBE2D, UBC4, UBC5ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K10573UBE2A, UBC2, RAD6Aubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 330879.Q4WLA7 in eggNOG.

OGTaxonomic classDescription
LCOG5078All organisms (root)ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24],ubiquitin-conjugating enzyme E2 I
FQI6PDikarya (subkingdom)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13,ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
KOG0419Eukaryota (superkingdom)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
BKXUSFungi (kingdom)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13,ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
9STNFAscomycota (phylum)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13,ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C3HH8Pezizomycotina (subphylum)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
CHK1REurotiomycetes (class)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
7AEW4Eurotiomycetidae (subclass)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
CK6JGEurotiales (order)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
7MQNFOpisthokonta (clade)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
CVT3BAspergillaceae (family)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13
AQNFXAspergillus (genus)ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23],MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: