Domains within Mandrillus leucophaeus protein A0A2K5YX79_MANLE (A0A2K5YX79)

Uncharacterized protein

Alternative representations: 1 /

Protein length369 aa
Source databaseUniProt
Identifiers A0A2K5YX79_MANLE, A0A2K5YX79, ENSMLEP00000020142.1, ENSMLEP00000020142, Q9UMX3-2, G7PKH7_MACFA, G7PKH7, Q53NU8_HUMAN, Q53NU8, G7N9E3_MACMU, G7N9E3
Source gene ENSMLEG00000034287

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Metazoa

Predicted functional partners

A0A2K5YX79_MANLE is shown as BOK in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BOK

Protein A0A2K5YX79_MANLE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04210Apoptosis
map04215Apoptosis - multiple species

KEGG orthologous groups

KONameDescription
K02561BOKBcl-2-related ovarian killer protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9568.ENSMLEP00000020142 in eggNOG.

OGTaxonomic classDescription
LKOG4728All organisms (root)Bcl-2-related ovarian killer protein,apoptosis regulator BAX,Bcl-2-like 1 (apoptosis regulator Bcl-X)
KOG4728Eukaryota (superkingdom)Bcl-2-related ovarian killer protein,apoptosis regulator BAX,Bcl-2-like 1 (apoptosis regulator Bcl-X)
HSSKUMetazoa (kingdom)Bcl-2-related ovarian killer protein,Bcl-2 family protein
93Y79Chordata (phylum)Bcl-2-related ovarian killer protein
5QKPVSarcopterygii (superclass)Bcl-2-related ovarian killer protein
8Z758Mammalia (class)Bcl-2-related ovarian killer protein
4R6Y2Euarchontoglires (superorder)Bcl-2-related ovarian killer protein
4ZQYIPrimates (order)Bcl-2-related ovarian killer protein
98ADMHaplorrhini (suborder)Bcl-2-related ovarian killer protein
BV2H5Simiiformes (infraorder)Bcl-2-related ovarian killer protein
9EPCRCatarrhini (parvorder)Bcl-2-related ovarian killer protein
9G5Q4Vertebrata (clade)Bcl-2-related ovarian killer protein
7NC8JOpisthokonta (clade)Bcl-2-related ovarian killer protein,Bcl-2 family protein
H5M4MBilateria (clade)Bcl-2-related ovarian killer protein,Bcl-2 family protein
6IAUTCercopithecidae (family)Bcl-2-related ovarian killer protein
BR72ACercopithecinae (subfamily)Bcl-2-related ovarian killer protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: