Domains within Mus musculus protein ALBU_MOUSE (P07724)

Serum albumin

Alternative representations: 1 /

Protein length608 aa
Source databaseUniProt
Identifiers ALBU_MOUSE, P07724, ENSMUSP00000031314.8, ENSMUSP00000031314, Q3TV03, Q61802, Q8C7C7, Q8C7H3, Q8CG74, Q546G4_MOUSE, Q546G4, C6KIA0_MUSCR, C6KIA0, K7R066_MOUSE, K7R066
Source gene ENSMUSG00000029368

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

ALBU_MOUSE is shown as Alb in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Alb

Protein ALBU_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04390Hippo signaling pathway
map04918Thyroid hormone synthesis

KEGG orthologous groups

KONameDescription
K16144AFPalpha-fetoprotein
K16141ALBserum albumin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 94 PTMs annotated in this protein:

PTMCount
Phosphorylation33
Acetylation28
N-linked glycosylation13
Glycation7
Ubiquitination5
Nitrosylation4
Proteolytic cleavage2
Methylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Alb.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000031314 in eggNOG.

OGTaxonomic classDescription
6T6FJAll organisms (root)alpha-fetoprotein,afamin,serum albumin
5EHBNEukaryota (superkingdom)alpha-fetoprotein,afamin,serum albumin
HSK6DMetazoa (kingdom)alpha-fetoprotein,serum albumin
94QXQChordata (phylum)alpha-fetoprotein,serum albumin
5QKMVSarcopterygii (superclass)alpha-fetoprotein,serum albumin
8ZC15Mammalia (class)alpha-fetoprotein,serum albumin
4RGHREuarchontoglires (superorder)serum albumin
AI4ZPRodentia (order)serum albumin
8DI9CMyomorpha (suborder)serum albumin
9GUIXVertebrata (clade)alpha-fetoprotein,serum albumin
7HVY6Opisthokonta (clade)alpha-fetoprotein,serum albumin
H4996Bilateria (clade)alpha-fetoprotein,serum albumin
CQ4TEMuridae (family)serum albumin
ADYGNMurinae (subfamily)serum albumin
5PFMEMus (genus)serum albumin
HE8AYMus (subgenus)serum albumin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: