Domains within Candida albicans SC5314 protein ARP4_CANAL (Q5AC48)

Actin-related protein 4

Alternative representations: 1 /

Protein length468 aa
Source databaseUniProt
Identifiers A0A1D8PQ46, Q5ABS7, ARP4_CANAL, Q5AC48

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ARP4_CANAL is shown as ARP4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ARP4

Protein ARP4_CANAL is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05132Salmonella infection
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K10355ACTFactin, other eukaryote
K11400ARP4actin-related protein 4
K11340ACTL6A, INO80Kactin-like protein 6A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 237561.Q5AC48 in eggNOG.

OGTaxonomic classDescription
LCOG5277All organisms (root)actin, other eukaryote,actin-related protein 3,actin-related protein 2
FSR1TDikarya (subkingdom)actin-related protein 4,actin-like protein 6B
KOG0679Eukaryota (superkingdom)actin-like protein 6A,actin-like protein 6B,actin-related protein 4
BK8K2Fungi (kingdom)actin-related protein 4,actin-like protein 6B
9TMR0Ascomycota (phylum)actin-related protein 4
91F81Saccharomycetales (order)actin-related protein 4
7GQXIOpisthokonta (clade)actin-like protein 6B,actin-like protein 6A,actin-related protein 4
66WYTDebaryomycetaceae (family)actin-related protein 4
BUHIQCandida (genus)actin-related protein 4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: