Domains within Mus musculus protein Q5D078_MOUSE (Q5D078)

Regulator of G-protein signaling 4

Alternative representations: 1 /

Protein length205 aa
Source databaseUniProt
Identifiers Q5D078_MOUSE, Q5D078, ENSMUSP00000027991.5, ENSMUSP00000027991
Source gene ENSMUSG00000038530
Alternative splicing Q5D078_MOUSE, D3YXR2_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q5D078_MOUSE is shown as Rgs4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Rgs4

Protein Q5D078_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K16449RGSregulator of G-protein signaling

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Methylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Rgs4.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000027991 in eggNOG.

OGTaxonomic classDescription
LKOG3589All organisms (root)regulator of G-protein signaling,axin 1,regulator of G-protein signaling 2
KOG3589Eukaryota (superkingdom)regulator of G-protein signaling,axin 1,regulator of G-protein signaling 2
HUGXGMetazoa (kingdom)regulator of G-protein signaling
93K8AChordata (phylum)regulator of G-protein signaling
5QZMFSarcopterygii (superclass)regulator of G-protein signaling
8Z905Mammalia (class)regulator of G-protein signaling
4RDZSEuarchontoglires (superorder)regulator of G-protein signaling
AI37QRodentia (order)regulator of G-protein signaling
8DB2SMyomorpha (suborder)regulator of G-protein signaling
H6H8MBilateria (clade)regulator of G-protein signaling
7N24XOpisthokonta (clade)regulator of G-protein signaling
9G7EBVertebrata (clade)regulator of G-protein signaling
CQ7VXMuridae (family)regulator of G-protein signaling
AE6RZMurinae (subfamily)regulator of G-protein signaling
5PH6RMus (genus)regulator of G-protein signaling
HE7I6Mus (subgenus)regulator of G-protein signaling

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: