Domains within Mus musculus protein ZFY26_MOUSE (Q5DU37)

Zinc finger FYVE domain-containing protein 26

Alternative representations: 1 /

Protein length2529 aa
Source databaseUniProt
Identifiers ZFY26_MOUSE, Q5DU37, ENSMUSP00000021547.6, ENSMUSP00000021547, B9EJ71, Q3TEM9, Q3V1N3, Q8BY74, Q8CDR8, Q923B4
Source gene ENSMUSG00000066440
Alternative splicing ZFY26_MOUSE, A0A1W2P6J0_MOUSE, A0A1W2P6K6_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ZFY26_MOUSE is shown as Zfyve26 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Zfyve26

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 28 PTMs annotated in this protein:

PTMCount
Phosphorylation22
Ubiquitination4
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Zfyve26.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000021547 in eggNOG.

OGTaxonomic classDescription
LKOG1811All organisms (root)zinc finger FYVE domain-containing protein 26,zinc finger FYVE domain-containing protein 21
KOG1811Eukaryota (superkingdom)zinc finger FYVE domain-containing protein 26,zinc finger FYVE domain-containing protein 21
HV7M4Metazoa (kingdom)zinc finger FYVE domain-containing protein 26
94VZEChordata (phylum)zinc finger FYVE domain-containing protein 26
5R05CSarcopterygii (superclass)zinc finger FYVE domain-containing protein 26
8Z64QMammalia (class)zinc finger FYVE domain-containing protein 26
4R5EXEuarchontoglires (superorder)zinc finger FYVE domain-containing protein 26
AI4WXRodentia (order)zinc finger FYVE domain-containing protein 26
8D6MPMyomorpha (suborder)zinc finger FYVE domain-containing protein 26
H3US6Bilateria (clade)zinc finger FYVE domain-containing protein 26
9GHC8Vertebrata (clade)zinc finger FYVE domain-containing protein 26
7HW2NOpisthokonta (clade)zinc finger FYVE domain-containing protein 26,zinc finger FYVE domain-containing protein 21
CQ2CKMuridae (family)zinc finger FYVE domain-containing protein 26
AE7CVMurinae (subfamily)zinc finger FYVE domain-containing protein 26
5PVZUMus (genus)zinc finger FYVE domain-containing protein 26
HE4HMMus (subgenus)zinc finger FYVE domain-containing protein 26

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: