Domains within Bos taurus protein C1QA_BOVIN (Q5E9E3)

Complement C1q subcomponent subunit A

Alternative representations: 1 /

Protein length244 aa
Source databaseUniProt
Identifiers C1QA_BOVIN, Q5E9E3, ENSBTAP00000009415.2, ENSBTAP00000009415, ENSBTAP00000039925.3, ENSBTAP00000039925, Q56JV0
Source gene ENSBTAG00000007153

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

C1QA_BOVIN is shown as C1QA in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for C1QA

Protein C1QA_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04974Protein digestion and absorption
map05142Chagas disease

KEGG orthologous groups

KONameDescription
K03986C1QAcomplement C1q subcomponent subunit A
K19721COL5AScollagen type V/XI/XXIV/XXVII, alpha

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 16 PTMs annotated in this protein:

PTMCount
Hydroxylation11
O-linked glycosylation4
N-linked glycosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein C1QA.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000009415 in eggNOG.

OGTaxonomic classDescription
LKOG3544All organisms (root)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
KOG3544Eukaryota (superkingdom)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
HTDHRMetazoa (kingdom)complement C1q subcomponent subunit A,complement C1q subcomponent subunit C,complement C1q subcomponent subunit B
93RUSChordata (phylum)complement C1q subcomponent subunit A,complement C1q subcomponent subunit C,complement C1q subcomponent subunit B
5R4A0Sarcopterygii (superclass)complement C1q subcomponent subunit A,complement C1q subcomponent subunit C,complement C1q subcomponent subunit B
8YUVVMammalia (class)complement C1q subcomponent subunit A
BQYD9Laurasiatheria (superorder)complement C1q subcomponent subunit A
AX2STArtiodactyla (order)complement C1q subcomponent subunit A
B60BGPecora (infraorder)complement C1q subcomponent subunit A
9G1F7Vertebrata (clade)complement C1q subcomponent subunit A,complement C1q subcomponent subunit C,complement C1q subcomponent subunit B
H4F17Bilateria (clade)complement C1q subcomponent subunit A,complement C1q subcomponent subunit C,complement C1q subcomponent subunit B
7HUXSOpisthokonta (clade)complement C1q subcomponent subunit A,complement C1q subcomponent subunit C,complement C1q subcomponent subunit B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: