Domains within Cryptococcus neoformans var. neoformans JEC21 protein Q5KNF0_CRYNJ (Q5KNF0)

Ubiquitin-protein ligase, putative

Alternative representations: 1 /

Protein length995 aa
Source databaseUniProt
Identifiers Q5KNF0_CRYNJ, Q5KNF0

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q5KNF0_CRYNJ is shown as Q5KNF0_CRYNJ in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Q5KNF0_CRYNJ

Protein Q5KNF0_CRYNJ is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis
map04111Cell cycle - yeast

KEGG orthologous groups

KONameDescription
K10260FBXW7, SEL10F-box and WD-40 domain protein 7
K03361CDC4F-box and WD-40 domain protein CDC4

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 214684.Q5KNF0 in eggNOG.

OGTaxonomic classDescription
LKOG0274All organisms (root)F-box and WD-40 domain protein 7,F-box and WD-40 domain protein CDC4,E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
FQZ6PDikarya (subkingdom)F-box and WD-40 domain protein CDC4,F-box and WD-40 domain protein 7,ferredoxin-2, mitochondrial
KOG0274Eukaryota (superkingdom)F-box and WD-40 domain protein 7,F-box and WD-40 domain protein CDC4,E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
BMBY0Fungi (kingdom)F-box and WD-40 domain protein CDC4,F-box and WD-40 domain protein 7,ferredoxin-2, mitochondrial
CSR3HBasidiomycota (phylum)F-box and WD-40 domain protein CDC4,ferredoxin-2, mitochondrial
DJYQ8Agaricomycotina (subphylum)F-box and WD-40 domain protein CDC4
7E7Q4Tremellomycetes (class)F-box and WD-40 domain protein CDC4
54RGETremellales (order)F-box and WD-40 domain protein CDC4
7GUDSOpisthokonta (clade)F-box and WD-40 domain protein 7,F-box and WD-40 domain protein CDC4,F-box and WD-40 domain protein 9
FZEPYCryptococcaceae (family)F-box and WD-40 domain protein CDC4
AEIFRCryptococcus (genus)F-box and WD-40 domain protein CDC4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: