Domains within Danio rerio protein 143BA_DANRE (Q5PRD0)

14-3-3 protein beta/alpha-A

Alternative representations: 1 /

Protein length244 aa
Source databaseUniProt
Identifiers 143BA_DANRE, Q5PRD0, ENSDARP00000027118.8, ENSDARP00000027118, A3KNI9, E9QJ96_DANRE, E9QJ96
Source gene ENSDARG00000013078
Alternative splicing 143BA_DANRE, ENSDARP00000122901.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

143BA_DANRE is shown as ywhaba in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ywhaba

Protein 143BA_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04110Cell cycle
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K06630YWHAE14-3-3 protein epsilon
K16197YWHAB_Q_Z14-3-3 protein beta/theta/zeta

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000027118 in eggNOG.

OGTaxonomic classDescription
LKOG0841All organisms (root)14-3-3 protein epsilon,14-3-3 protein beta/theta/zeta,14-3-3 protein gamma/eta
9IW5NOtomorpha (cohort)14-3-3 protein beta/theta/zeta
KOG0841Eukaryota (superkingdom)14-3-3 protein epsilon,14-3-3 protein beta/theta/zeta,14-3-3 protein gamma/eta
HTW5KMetazoa (kingdom)14-3-3 protein beta/theta/zeta,14-3-3 protein gamma/eta,14-3-3 protein epsilon
93U3SChordata (phylum)14-3-3 protein beta/theta/zeta,14-3-3 protein epsilon,stratifin
FXYEGActinopterygii (superclass)14-3-3 protein beta/theta/zeta
8N1WYNeopterygii (subclass)14-3-3 protein beta/theta/zeta
7MCZTOpisthokonta (clade)14-3-3 protein beta/theta/zeta,14-3-3 protein epsilon,14-3-3 protein gamma/eta
9FSVRVertebrata (clade)14-3-3 protein beta/theta/zeta,stratifin,14-3-3 protein epsilon
H6YS7Bilateria (clade)14-3-3 protein beta/theta/zeta,14-3-3 protein gamma/eta,14-3-3 protein epsilon
BETM8Cyprinidae (family)14-3-3 protein beta/theta/zeta

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: