Domains within Homo sapiens protein P210L_HUMAN (Q5VU65)

Nuclear pore membrane glycoprotein 210-like

Alternative representations: 1 /

Protein length1888 aa
Source databaseUniProt
Identifiers P210L_HUMAN, Q5VU65, ENSP00000357547.3, ENSP00000357547, E7EP56, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6, Q9UF31
Source gene ENSG00000143552
Alternative splicing P210L_HUMAN, X6R6V8_HUMAN, ENSP00000271854.3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

P210L_HUMAN is shown as NUP210L in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NUP210L

Protein P210L_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03013Nucleocytoplasmic transport

KEGG orthologous groups

KONameDescription
K14314NUP210, GP210nuclear pore complex protein Nup210

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 27 PTMs annotated in this protein:

PTMCount
Phosphorylation14
N-linked glycosylation6
Ubiquitination5
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein DKFZp434E2118.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000357547 in eggNOG.

OGTaxonomic classDescription
LKOG1833All organisms (root)nuclear pore complex protein Nup210,Ras-related protein Rab-13
KOG1833Eukaryota (superkingdom)nuclear pore complex protein Nup210,Ras-related protein Rab-13
HVWIPMetazoa (kingdom)nuclear pore complex protein Nup210,Ras-related protein Rab-13
942TXChordata (phylum)nuclear pore complex protein Nup210,Ras-related protein Rab-13
5R90KSarcopterygii (superclass)nuclear pore complex protein Nup210,Ras-related protein Rab-13
8Z46XMammalia (class)nuclear pore complex protein Nup210,Ras-related protein Rab-13
4RHFHEuarchontoglires (superorder)nuclear pore complex protein Nup210,Ras-related protein Rab-13
4ZXQ7Primates (order)nuclear pore complex protein Nup210
98ARZHaplorrhini (suborder)nuclear pore complex protein Nup210
BV06ISimiiformes (infraorder)nuclear pore complex protein Nup210
9EGUSCatarrhini (parvorder)nuclear pore complex protein Nup210
7KNCGOpisthokonta (clade)nuclear pore complex protein Nup210,Ras-related protein Rab-13
9GR6EVertebrata (clade)nuclear pore complex protein Nup210,Ras-related protein Rab-13
H4VBQBilateria (clade)nuclear pore complex protein Nup210,Ras-related protein Rab-13
FX0F9Hominoidea (superfamily)nuclear pore complex protein Nup210
5MZHNHominidae (family)nuclear pore complex protein Nup210
5Y5DDHomininae (subfamily)nuclear pore complex protein Nup210

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: