Domains within Mus musculus protein SIN3A_MOUSE (Q60520)

Paired amphipathic helix protein Sin3a

Alternative representations: 1 /

Protein length1274 aa
Source databaseUniProt
Identifiers SIN3A_MOUSE, Q60520, ENSMUSP00000130641.1, ENSMUSP00000130641, ENSMUSP00000126601.1, ENSMUSP00000126601, ENSMUSP00000045044.5, ENSMUSP00000045044, Q570Z7, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2, Q3UVS7_MOUSE, Q3UVS7
Source gene ENSMUSG00000042557
Alternative splicing ENSMUSP00000129062.1, SIN3A_MOUSE, ENSMUSP00000130221.1, E9PXF9_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

SIN3A_MOUSE is shown as Sin3a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Sin3a

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10103.ENSMSIP00000010402 in eggNOG.

OGTaxonomic classDescription
LKOG4204All organisms (root)paired amphipathic helix protein Sin3a,paired amphipathic helix protein Sin3b,20S proteasome subunit beta 5 [EC:3.4.25.1]
KOG4204Eukaryota (superkingdom)paired amphipathic helix protein Sin3a,paired amphipathic helix protein Sin3b,20S proteasome subunit beta 5 [EC:3.4.25.1]
HVBP7Metazoa (kingdom)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
93ZBBChordata (phylum)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
5R7PMSarcopterygii (superclass)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
8ZC4IMammalia (class)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
4RB7GEuarchontoglires (superorder)paired amphipathic helix protein Sin3a
AIBQSRodentia (order)paired amphipathic helix protein Sin3a
8DFWIMyomorpha (suborder)paired amphipathic helix protein Sin3a
9GT1RVertebrata (clade)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
H3STSBilateria (clade)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
7MKSDOpisthokonta (clade)paired amphipathic helix protein Sin3b,paired amphipathic helix protein Sin3a,NACHT domain- and WD repeat-containing protein
CQCYHMuridae (family)paired amphipathic helix protein Sin3a
AE5QGMurinae (subfamily)paired amphipathic helix protein Sin3a
5PGKQMus (genus)paired amphipathic helix protein Sin3a
HE2KXMus (subgenus)paired amphipathic helix protein Sin3a

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: