Domains within Mus musculus protein XRCC1_MOUSE (Q60596)

DNA repair protein XRCC1

Alternative representations: 1 /

Protein length631 aa
Source databaseUniProt
Identifiers XRCC1_MOUSE, Q60596, ENSMUSP00000146105.1, ENSMUSP00000146105, ENSMUSP00000070995.8, ENSMUSP00000070995, Q3THC5, Q5U435, Q7TNQ5
Source gene ENSMUSG00000051768

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

XRCC1_MOUSE is shown as Xrcc1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Xrcc1

Protein XRCC1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03410Base excision repair

KEGG orthologous groups

KONameDescription
K10803XRCC1DNA-repair protein XRCC1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 43 PTMs annotated in this protein:

PTMCount
Phosphorylation37
Acetylation5
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Xrcc1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000146105 in eggNOG.

OGTaxonomic classDescription
LKOG3226All organisms (root)DNA-repair protein XRCC1,transient receptor potential cation channel subfamily C member 2
KOG3226Eukaryota (superkingdom)DNA-repair protein XRCC1,transient receptor potential cation channel subfamily C member 2
HUW7AMetazoa (kingdom)DNA-repair protein XRCC1,transient receptor potential cation channel subfamily C member 2
94QPFChordata (phylum)DNA-repair protein XRCC1
5QNS3Sarcopterygii (superclass)DNA-repair protein XRCC1
8Z3RKMammalia (class)DNA-repair protein XRCC1
4R2YGEuarchontoglires (superorder)DNA-repair protein XRCC1
AID7NRodentia (order)DNA-repair protein XRCC1
8D9K0Myomorpha (suborder)DNA-repair protein XRCC1
7H47QOpisthokonta (clade)DNA-repair protein XRCC1,transient receptor potential cation channel subfamily C member 2
9GDWKVertebrata (clade)DNA-repair protein XRCC1
H4ZEYBilateria (clade)DNA-repair protein XRCC1
CQ0AFMuridae (family)DNA-repair protein XRCC1
ADWHJMurinae (subfamily)DNA-repair protein XRCC1
5PVN7Mus (genus)DNA-repair protein XRCC1
HE7VYMus (subgenus)DNA-repair protein XRCC1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: