Domains within Mus musculus protein TCF15_MOUSE (Q60756)

Transcription factor 15

Alternative representations: 1 /

Protein length195 aa
Source databaseUniProt
Identifiers TCF15_MOUSE, Q60756, ENSMUSP00000086511.5, ENSMUSP00000086511, Q60788
Source gene ENSMUSG00000068079

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

TCF15_MOUSE is shown as Tcf15 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Tcf15

Protein TCF15_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04550Signaling pathways regulating pluripotency of stem cells

KEGG orthologous groups

KONameDescription
K09067ASCLachaete-scute complex protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Tcf15.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000086511 in eggNOG.

OGTaxonomic classDescription
LKOG4029All organisms (root)achaete-scute complex protein,T-cell acute lymphocytic leukemia protein,nescient helix-loop-helix protein
KOG4029Eukaryota (superkingdom)achaete-scute complex protein,T-cell acute lymphocytic leukemia protein,nescient helix-loop-helix protein
HVECFMetazoa (kingdom)transcription factor 15
93N7WChordata (phylum)transcription factor 15
5QGFESarcopterygii (superclass)transcription factor 15
8Z8JNMammalia (class)transcription factor 15
4RKDGEuarchontoglires (superorder)transcription factor 15
AI1E0Rodentia (order)transcription factor 15
8DKWKMyomorpha (suborder)transcription factor 15
7KTMROpisthokonta (clade)transcription factor 15
9FABRVertebrata (clade)transcription factor 15
H4H51Bilateria (clade)transcription factor 15
CQ9Y9Muridae (family)transcription factor 15
AE6YKMurinae (subfamily)transcription factor 15
5PV0AMus (genus)transcription factor 15
HEAPMMus (subgenus)transcription factor 15

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: