Domains within Mus musculus protein HCFC1_MOUSE (Q61191)

Host cell factor 1

Alternative representations: 1 /

Protein length2045 aa
Source databaseUniProt
Identifiers HCFC1_MOUSE, Q61191, ENSMUSP00000033761.6, ENSMUSP00000033761, B1AUX1, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2
Source gene ENSMUSG00000031386
Alternative splicing HCFC1_MOUSE, F6SJS2_MOUSE, B1AUX2_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

HCFC1_MOUSE is shown as Hcfc1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Hcfc1

Protein HCFC1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04212Longevity regulating pathway - worm

KEGG orthologous groups

KONameDescription
K14966HCFC1host cell factor 1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000033761 in eggNOG.

OGTaxonomic classDescription
LKOG4152All organisms (root)host cell factor,Rab9 effector protein with kelch motifs,clock-associated PAS protein ZTL
KOG4152Eukaryota (superkingdom)host cell factor,Rab9 effector protein with kelch motifs,clock-associated PAS protein ZTL
HUYV2Metazoa (kingdom)host cell factor
93VS4Chordata (phylum)host cell factor
5QV17Sarcopterygii (superclass)host cell factor
8ZN56Mammalia (class)host cell factor
4RK7DEuarchontoglires (superorder)host cell factor
AI9ZJRodentia (order)host cell factor
8DFA8Myomorpha (suborder)host cell factor
9GA3CVertebrata (clade)host cell factor
7IJ2HOpisthokonta (clade)host cell factor
H5K7VBilateria (clade)host cell factor
CQFG6Muridae (family)host cell factor
ADZ51Murinae (subfamily)host cell factor
5PRYBMus (genus)host cell factor
HE658Mus (subgenus)host cell factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: