Domains within Mus musculus protein DLL1_MOUSE (Q61483)

Delta-like protein 1

Alternative representations: 1 /

Protein length722 aa
Source databaseUniProt
Identifiers DLL1_MOUSE, Q61483, ENSMUSP00000014917.7, ENSMUSP00000014917, Q6PFV7
Source gene ENSMUSG00000014773

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

DLL1_MOUSE is shown as Dll1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Dll1

Protein DLL1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection
map05200Pathways in cancer

KEGG orthologous groups

KONameDescription
K00430E1.11.1.7peroxidase [EC:1.11.1.7] iPath3
K04659THBS2Sthrombospondin 2/3/4/5
K06051DLLdelta
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
Phosphorylation1
Methylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Dll1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000014917 in eggNOG.

OGTaxonomic classDescription
7553HAll organisms (root)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
KOG1217Eukaryota (superkingdom)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
HSY91Metazoa (kingdom)thrombospondin 2/3/4/5,delta,matrilin
93GJ3Chordata (phylum)delta
5QCQJSarcopterygii (superclass)delta
8YXFCMammalia (class)delta
4RIXHEuarchontoglires (superorder)delta
AIF4ARodentia (order)delta
8DDBCMyomorpha (suborder)delta
9GHYNVertebrata (clade)delta
7NXWDOpisthokonta (clade)thrombospondin 2/3/4/5,delta,matrilin
H4QFHBilateria (clade)thrombospondin 2/3/4/5,delta,matrilin
CQG0EMuridae (family)delta
AE53JMurinae (subfamily)delta
5PKFUMus (genus)delta
HEAU6Mus (subgenus)delta

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: