Domains within Rattus norvegicus protein CLK3_RAT (Q63117)

Dual specificity protein kinase CLK3

Alternative representations: 1 /

Protein length490 aa
Source databaseUniProt
Identifiers CLK3_RAT, Q63117, ENSRNOP00000061691.1, ENSRNOP00000061691, ENSRNOP00000072998.1, ENSRNOP00000072998, Q6IRK2
Source gene ENSRNOG00000030126

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CLK3_RAT is shown as Clk3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Clk3

Protein CLK3_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05134Legionellosis

KEGG orthologous groups

KONameDescription
K08823CLK2_3dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
K23561CLK1_4dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
K08287E2.7.12.1dual-specificity kinase [EC:2.7.12.1]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000061691 in eggNOG.

OGTaxonomic classDescription
LKOG0671All organisms (root)dual-specificity kinase [EC:2.7.12.1],dual specificity protein kinase CLK2/3 [EC:2.7.12.1],dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
KOG0671Eukaryota (superkingdom)dual-specificity kinase [EC:2.7.12.1],dual specificity protein kinase CLK2/3 [EC:2.7.12.1],dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
HTWATMetazoa (kingdom)dual specificity protein kinase CLK2/3 [EC:2.7.12.1],dual specificity protein kinase CLK1/4 [EC:2.7.12.1],secretory carrier-associated membrane protein
94N57Chordata (phylum)dual specificity protein kinase CLK1/4 [EC:2.7.12.1],dual specificity protein kinase CLK2/3 [EC:2.7.12.1],secretory carrier-associated membrane protein
5QWQ0Sarcopterygii (superclass)dual specificity protein kinase CLK1/4 [EC:2.7.12.1],dual specificity protein kinase CLK2/3 [EC:2.7.12.1],secretory carrier-associated membrane protein
8Z3RFMammalia (class)dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
4R9B1Euarchontoglires (superorder)dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
AHZ3IRodentia (order)dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
8DKS4Myomorpha (suborder)dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
H4JCRBilateria (clade)dual specificity protein kinase CLK2/3 [EC:2.7.12.1],dual specificity protein kinase CLK1/4 [EC:2.7.12.1],secretory carrier-associated membrane protein
7GYU7Opisthokonta (clade)dual specificity protein kinase CLK2/3 [EC:2.7.12.1],dual specificity protein kinase CLK1/4 [EC:2.7.12.1],dual-specificity kinase [EC:2.7.12.1]
9FFUVVertebrata (clade)dual specificity protein kinase CLK1/4 [EC:2.7.12.1],dual specificity protein kinase CLK2/3 [EC:2.7.12.1],secretory carrier-associated membrane protein
CQAAAMuridae (family)dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
AE15EMurinae (subfamily)dual specificity protein kinase CLK2/3 [EC:2.7.12.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: