Domains within Mus musculus protein HECAM_MOUSE (Q640R3)

Hepatocyte cell adhesion molecule

Alternative representations: 1 /

Protein length418 aa
Source databaseUniProt
Identifiers HECAM_MOUSE, Q640R3, ENSMUSP00000054105.7, ENSMUSP00000054105, B2RSY3_MOUSE, B2RSY3
Source gene ENSMUSG00000046240
Alternative splicing HECAM_MOUSE, A0A1L1SUR4_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

HECAM_MOUSE is shown as Hepacam in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Hepacam

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 15 PTMs annotated in this protein:

PTMCount
Phosphorylation14
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Hepacam.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000054105 in eggNOG.

OGTaxonomic classDescription
6Y2WFAll organisms (root)hepatocyte cell adhesion molecule
5IYJ8Eukaryota (superkingdom)hepatocyte cell adhesion molecule
HTGH6Metazoa (kingdom)hepatocyte cell adhesion molecule
94927Chordata (phylum)hepatocyte cell adhesion molecule
5R4F8Sarcopterygii (superclass)hepatocyte cell adhesion molecule
8ZEH5Mammalia (class)hepatocyte cell adhesion molecule
4R65GEuarchontoglires (superorder)hepatocyte cell adhesion molecule
AI9N7Rodentia (order)hepatocyte cell adhesion molecule
8D8U3Myomorpha (suborder)hepatocyte cell adhesion molecule
9GIBZVertebrata (clade)hepatocyte cell adhesion molecule
H5IEMBilateria (clade)hepatocyte cell adhesion molecule
7MM36Opisthokonta (clade)hepatocyte cell adhesion molecule
CQ8AAMuridae (family)hepatocyte cell adhesion molecule
AECNJMurinae (subfamily)hepatocyte cell adhesion molecule
5PU1YMus (genus)hepatocyte cell adhesion molecule
HEGENMus (subgenus)hepatocyte cell adhesion molecule

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: